Results 161 to 170 of about 678,102 (350)
Extremely high levels of vancomycin can cause severe renal toxicity
Infection and Drug Resistance, 2018 Jaime Barceló-Vidal,1 Eva Rodríguez-García,2 Santiago Grau3 1Department of Pharmacy, Hospital del Mar, Parc de Salut Mar, Barcelona, Spain; 2Department of Nephrology, Hospital del Mar, Parc de Salut Mar, Barcelona, Spain; 3Department
Barceló-Vidal J +2 more
doaj
Pharmacy Newsletter : October 2007 [PDF]
, 2007 Content: Management of Scorpion Envenomation Managing Toxic Methanol Poisoning Facts on Therapeutic Drug Monitoring Adverse Drug Reaction Updatehttps://ecommons.aku.edu/pharmacy_newsletter/1019/thumbnail ...
Pharmacy Department,
core +1 more source
Determination of ADP/ATP translocase isoform ratios in malignancy and cellular senescence
Molecular Oncology, EarlyView.The individual functions of three isoforms exchanging ADP and ATP (ADP/ATP translocases; ANTs) on the mitochondrial membrane remain unclear. We developed a method for quantitatively differentiating highly similar human ANT1, ANT2, and ANT3 using parallel reaction monitoring. This method allowed us to assess changes in translocase levels during cellular
Zuzana Liblova +18 more
wiley +1 more source
Molecular Oncology, EarlyView.Breast cancer metastasis is associated with myeloid cell dysregulation and the lung‐specific accumulation of tumor‐supportive Gr1+ cells. Gr1+ cells support metastasis, in part, through a CHI3L1‐mediated mechanism, which can be targeted and inhibited with cargo‐free, polymeric nanoparticles.
Jeffrey A. Ma +9 more
wiley +1 more source
Therapeutic drug monitoring of biologics in psoriasis
Biologics: Targets & Therapy, 2019 MeiQi May Liau,1 Hazel H Oon2 1Division of Dermatology, University Medicine Cluster, National University Hospital, Singapore; 2National Skin Centre, Singapore Abstract: Biologics are an important component of the armamentarium of drugs in the treatment ...
Liau MM, Oon HH
doaj
Decoding Drug Discovery: Exploring A-to-Z In silico Methods for Beginners [PDF]
The drug development process is a critical challenge in the pharmaceutical industry due to its time-consuming nature and the need to discover new drug potentials to address various ailments. The initial step in drug development, drug target identification, often consumes considerable time.
arxiv +1 more source
Understanding and measuring mechanical signals in the tumor stroma
FEBS Open Bio, EarlyView.This review discusses cancer‐associated fibroblast subtypes and their functions, particularly in relation to extracellular matrix production, as well as the development of 3D models to study tumor stroma mechanics in vitro. Several quantitative techniques to measure tissue mechanical properties are also described, to emphasize the diagnostic and ...
Fàtima de la Jara Ortiz +3 more
wiley +1 more source
Challenging Recommended Oral and Intravenous Voriconazole Doses for Improved Efficacy and Safety: Population Pharmacokinetics-Based Analysis of Adult Patients With Invasive Fungal Infections [PDF]
, 2017 This population-pharmacokinetics analysis involving adult patients with invasive fungal infections challenges recommended voriconazole dosing regimens. Higher oral than intravenous doses, followed by individualized adjustments based on therapeutic drug ...
Bille, Jacques +6 more
core
Therapeutic drug monitoring in a developing country: an overview [PDF]
, 1999 Gogtay, Kshirsagar, Dalvi
openalex +1 more source
FEBS Open Bio, EarlyView.This review highlights how foundation models enhance predictive healthcare by integrating advanced digital twin modeling with multiomics and biomedical data. This approach supports disease management, risk assessment, and personalized medicine, with the goal of optimizing health outcomes through adaptive, interpretable digital simulations, accessible ...
Sakhaa Alsaedi +2 more
wiley +1 more source