Results 301 to 310 of about 678,102 (350)

Consolidate Overview of Ribonucleic Acid Molecular Dynamics: From Molecular Movements to Material Innovations

Advanced Engineering Materials, EarlyView.
Molecular dynamics simulations are advancing the study of ribonucleic acid (RNA) and RNA‐conjugated molecules. These developments include improvements in force fields, long‐timescale dynamics, and coarse‐grained models, addressing limitations and refining methods.
Kanchan Yadav, Iksoo Jang, Jong Bum Lee
wiley   +1 more source

Pharmacogenetic Testing or Therapeutic Drug Monitoring: A Quantitative Framework. [PDF]

Clin Pharmacokinet
Centanni M, Reijnhout N, Thijs A, Karlsson MO, Friberg LE.   +4 more
europepmc   +1 more source

Beyond Order: Perspectives on Leveraging Machine Learning for Disordered Materials

Advanced Engineering Materials, EarlyView.
This article explores how machine learning (ML) revolutionizes the study and design of disordered materials by uncovering hidden patterns, predicting properties, and optimizing multiscale structures. It highlights key advancements, including generative models, graph neural networks, and hybrid ML‐physics methods, addressing challenges like data ...
Hamidreza Yazdani Sarvestani, Surabhi Nadigotti, Erfan Fatehi, Derek Aranguren van Egmond, Behnam Ashrafi   +4 more
wiley   +1 more source

Case report: Therapeutic drug monitoring and CYP2D6 phenoconversion in a protracted paroxetine intoxication. [PDF]

Front Pharmacol
Damborská A, Hanáková L, Pindurová E, Horská K.   +3 more
europepmc   +1 more source

Scalable Manufacturing of Radiation‐Tolerant Potentiometric Electrodes: A Systematic Transition from Laboratory to Semiautomated Fabrication

Advanced Engineering Materials, EarlyView.
Laboratory protocols for producing thin‐film pH electrodes for sterilized single‐use technologies have been successfully developed into a semiautomated workflow, with higher throughput and precision of membrane thickness. Accuracies are within 0.05 pH units versus ground truth, and uncertainty analysis reveals the largest sources of error to be derived
Bingyuan Zhao, Aiganym Yermembetova, Benson Kunhung Tsai, Jialong Huang, Alexander Wei   +4 more
wiley   +1 more source

Efficacy and Safety Assessment of Antifungal Prophylaxis with Posaconazole Using Therapeutic Drug Monitoring in Pediatric Patients with Oncohematological Disorders-A Single-Centre Study. [PDF]

J Fungi (Basel)
Liszka K, Marschollek P, Przystupski D, Frączkiewicz J, Mielcarek-Siedziuk M, Olejnik I, Gamrot Z, Haze N, Kwella A, Zalewska P, Resztak M, Ussowicz M, Kałwak K.   +12 more
europepmc   +1 more source

A Novel Protein‐Polysaccharide Oral Nanoemulsion Targeting Activated Hepatic Stellate Cells to Enhance the Therapeutic Effect of Pirfenidone on Fibrosis After Transarterial Chemoembolization for Liver Cancer

Advanced Functional Materials, EarlyView.
Transarterial Chemoembolization (TACE) may aggravate liver fibrosis. In this study, a novel oral targeting nanoemulsion is fabricated to enhance the therapeutic effect of antifibrotic drug‐pirfenidone (PFD) on fibrosis after TACE. Studies have shown that PFD nanoemulsion can enhance the oral liver targeting effect of PFD, and effectively improve the ...
Zhimei Cheng, Shan Xu, Yi Lei, Huizhou He, Runbin Sun, Xingle Jin, Cheneryu Huang, Yuhao Zheng, Jianqing Peng, Lei Tang, Peng Luo, Yi Chen, Shuai Zhang   +12 more
wiley   +1 more source

High-performance liquid chromatography-tandem mass spectrometry for simultaneous determination of 23 antidepressants and active metabolites in human serum and its application in therapeutic drug monitoring. [PDF]

Front Pharmacol
Wang J, Wang J, Zhang C, Li G.
europepmc   +1 more source

Therapeutic Drug Monitoring-Guided Linezolid Therapy for the Treatment of Multiple Staphylococcal Brain Abscesses in a 3-Month-Old Infant. [PDF]

Pathogens
Cascone A, De Luca M, Simeoli R, Goffredo BM, Cursi L, Tripiciano C, Romani L, Mercadante S, Di Giuseppe M, Calo Carducci FI, Luglietto D, Bernaschi P, Lancella L.   +12 more
europepmc   +1 more source