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[Therapeutic drug monitoring of antimicrobials].

Nederlands tijdschrift voor geneeskunde, 2014
Contains fulltext : 136169.pdf (Publisher’s version ) (Closed access)
Mouton, J.W., Aarnoutse, R.E.
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Therapeutic Drug Monitoring in Saliva

Clinical Pharmacokinetics, 1978
The observation that drug concentrations in saliva are often proportional to the concentrations in plasma has led to the suggestion that in therapeutic drug monitoring, or in pharmacokinetic studies in general, saliva might be substituted for plasma.
Meindert Danhof, D. D. Breimer
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Therapeutic Drug Monitoring of the Antimycobacterial Drugs

Clinics in Laboratory Medicine, 1996
Because MDR tuberculosis and MAC are difficult to treat, TDM with the antimycobacterial drugs has become the standard of practice at NJC. By combining specific and sensitive assays, carefully collected samples, and clinical expertise, we are able to control and optimize antimycobacterial drug therapy.
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Therapeutic drug monitoring in neonates

Archives of Disease in Childhood, 2016
Therapeutic drug monitoring (TDM) aims to integrate drug measurement results into clinical decision making. The basic rules apply when using TDM in neonates (aminoglycosides, vancomycin, phenobarbital, digoxin), but additional factors should also be taken into account.
Karel Allegaert, Steven Pauwels
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THERAPEUTIC DRUG MONITORING IN THE ELDERLY

American Journal of Therapeutics, 1996
Therapeutic drug monitoring (TDM) is defined as the strategy by which the dosing regimen for a patient is guided by repealed measurements of plasma drug concentrations. TDM is also used to confirm drug poisoning and toxicity, to diagnose adverse drug reactions, and to verify patient compliance with drug regimens.
David T. Lowenthal, Jorge G. Ruiz, Samir Array   +2 more
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Principles of therapeutic drug monitoring

Postgraduate Medicine, 1981
Biochemical monitoring is generally advised for drugs that are potentially toxic, have a narrow therapeutic range, or are prescribed for life-threatening disease. Monitoring should not be attempted until the serum concentration reaches a plateau, or steady state, and sampling must be timed carefully.
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Therapeutic drug monitoring

Clinical Pharmacology and Therapeutics, 1988
R, Spector, G D, Park, G F, Johnson, E S, Vesell   +3 more
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Introduction to therapeutic drug monitoring

2007
Therapeutic drug monitoring is useful for individual dosage adjustment and avoiding drug toxicity for certain drugs with a narrow therapeutic window. However, only relatively few drugs require therapeutic drug monitoring and most of these drugs are used for treating a chronic condition.
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Principles of Therapeutic Drug Monitoring

2011
Therapeutic drug monitoring (TDM) is central to optimize drug efficacy in children, because the pharmacokinetics and pharmacodynamics of most drugs differ greatly between children and adults. Many factors should be analyzed to implement TDM in the pediatric population, including a validated pharmacological parameter and an analytical method adapted to ...
Evelyne Jacqz-Aigrain, Wei Zhao
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Therapeutic drug monitoring for immunosuppressants

Clinica Chimica Acta, 2001
Immunosuppressants have significantly increased patient survival, e.g. in renal transplant up to 90% for the first year.Four immunosuppressants are used for clinical applications in the United States: cyclosporine (CsA) (Sandimmune and Neoral), FK 506-tacrolimus (ProGraf), mycophenolic mofetil (CellCept)--the prodrug for the mycophenolic acid (MPA ...
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