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Optimization of Antimicrobial Stewardship Programs Using Therapeutic Drug Monitoring and Pharmacokinetics–Pharmacodynamics Protocols: A Cost-Benefit Review

Therapeutic Drug Monitoring, 2023
Purpose: Antimicrobial stewardship programs are important for reducing antimicrobial resistance because they can readjust antibiotic prescriptions to local guidelines, switch intravenous to oral administration, and reduce hospitalization times ...
J. Telles   +9 more
semanticscholar   +1 more source

Therapeutic Drug Monitoring of Antibiotics: Defining the Therapeutic Range

Therapeutic Drug Monitoring, 2021
Purpose: In the present narrative review, the authors aimed to discuss the relationship between the pharmacokinetic/pharmacodynamic (PK/PD) of antibiotics and clinical response (including efficacy and toxicity).
M. Abdul-Aziz   +3 more
semanticscholar   +1 more source

A guide to therapeutic drug monitoring of β‐lactam antibiotics

Pharmacotherapy, 2021
Therapeutic drug monitoring (TDM) opens the door to personalized medicine, yet it is infrequently applied to β‐lactam antibiotics, one of the most commonly prescribed drug classes in the hospital setting.
A. Fratoni, D. Nicolau, J. Kuti
semanticscholar   +1 more source

Therapeutic drug monitoring

Acta Neuropsychiatrica, 1999
SUMMARYThe cytochrome P450 iso-enzyme system plays a key role in the biotransformation of many drugs, including psychotropics. Its activity is determined by both genetic and environmental factors. The most important iso-enzymes for psychiatry in general are P450 IID6, 3A4 and 1A2.
J B, Noten   +3 more
openaire   +2 more sources

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