Results 281 to 290 of about 18,835 (320)
Some of the next articles are maybe not open access.
Methodological standards for assessing therapeutic equivalence
Journal of Clinical Epidemiology, 1991This paper reviews issues related to defining and demonstrating therapeutic equivalence. A set of guidelines are proposed to critically review clinical trials to determine whether there is sufficient evidence to conclude that an experimental therapy is therapeutically equivalent to a standard one. These guidelines include criteria for assessing whether
openaire +2 more sources
Therapeutic reliability of variously manufactured drugs: Generic-therapeutic equivalence
The Journal of Pediatrics, 1970U N T I L recently we were in blissful ignorancC if we believed that all dosage forms of a particular drug could be expected to deliver the active ingredient to patients in an equivalent fashion. If this were so; we could ignore dosage form and use tablets, capsules, syrups, or elixirs interchangeably.
openaire +2 more sources
On Therapeutic Equivalency and the Antisubstitution Laws
JAMA: The Journal of the American Medical Association, 1973The comparative bioavailability of a drug in similarly formulated preparations is becoming a subject of considerable interest and importance to the physician. Drugs usually are not administered as pure compounds but are combined with materials such as binders, excipients, lubricants, preservatives, or other substances generally considered to be ...
openaire +2 more sources
[The concept of therapeutic equivalence].
Medizinische Klinik (Munich, Germany : 1983), 1997Usually, it is the purpose of a clinical trial to demonstrate the superiority of a (new) treatment in comparison to another treatment with regard to a well-defined criterion of efficacy. However, other aspects rather than improved efficacy might be regarded as advantages of a new therapy, i.e.
S, Lange, J, Windeler
openaire +1 more source
Drug Safety, 1996
For economic reasons, the use of generic substitution is increasingly being supported by health authorities. Potentially, this may be problematic for drugs with a narrow therapeutic window if quality control and/or bioequivalence is not optimal. Many developing countries do not have the resources or expertise to carry out appropriate quality control ...
openaire +2 more sources
For economic reasons, the use of generic substitution is increasingly being supported by health authorities. Potentially, this may be problematic for drugs with a narrow therapeutic window if quality control and/or bioequivalence is not optimal. Many developing countries do not have the resources or expertise to carry out appropriate quality control ...
openaire +2 more sources
Biologic Availability and Therapeutic Equivalence
The Journal of Clinical Pharmacology, 1976J D, Arnold, J, Sicé
openaire +2 more sources
Therapeutic equivalents in clinical practice.
International journal of fertility and women's medicine, 2001With increasing debate over the rising expenses of health care, a variety of cost-saving measures has been attempted over the years. Use of primary care physicians as "gate keepers," reduction in the length of hospital stays, and pushing women toward vaginal birth after Cesarean section have all been utilized despite on going issues with patient ...
openaire +1 more source
Therapeutic equivalence of mesalamine products.
Reviews in gastroenterological disorders, 2004No bioequivalence studies have been conducted for mesalamine because of differences in formulation. Based on U.S. Food and Drug Administration definitions for bioequivalence, none of these drugs can be classified as bioequivalent or therapeutically equivalent.
openaire +1 more source