Results 21 to 30 of about 5,258 (286)

Degradable poly(catechin) nanoparticles as a versatile therapeutic agent

, 2021
Poly(catechin) (p(CAT)) nanoparticles (NPs), 173 +/- 4 nm was prepared as a therapeutic agent with hydrolytic degradability affording sustainable CAT release over 20 d at carcinogenic conditions, pH 5.5 and 37.5 degrees C.
Ayyala, Ramesh S., Sahiner, Nurettin, Bhethanabotla, Venkat R., Mohapatra, Subhra, Suner, Selin S., Sahiner, Mehtap   +5 more
core   +1 more source

Safety and efficacy of simplified antibiotic regimens for outpatient treatment of serious infection in neonates and young infants 0-59 days of age in Bangladesh: design of a randomized controlled trial. [PDF]

, 2013
BACKGROUND: Because access to care is limited in settings with high mortality, exclusive reliance on the current recommendation of 7-10 days of parenteral antibiotic treatment is a barrier to provision of adequate treatment of newborn infections. METHODS:
Ahmed, Wazir, Cousens, Simon, Black, Robert E, Baqui, Abdullah H, Roth, Daniel E, Mullany, Luke C, Saha, Samir Kumar, Mitra, Dipak, Shahidullah, Mohammad, Quasem, Iftekhar, Wall, Stephen, Williams, Emma K, Ahmed, ASM Nawshad Uddin, Brandes, Neal, Shamsuzzaman, AKM   +14 more
core   +1 more source

Comparative Analysis of Nuclear Transfer Embryo Derived Mouse Embryonic Stem Cells. Part I: Cellular characterization [PDF]

, 2012
Embryonic stem cells derived from nuclear transfer embryos (ntESCs) are particularly valuable for regenerative medicine, as they are a patient-specific and histocompatible cell source for the treatment of varying diseases.
Julianna Kobolak, Ruttachuk Rungsiwiwut, Andras Dinnyes, Mamo, Solomon, Ujhelly, Olga, Csonka, Erika, Solomon Mamo, Hadlaczky, Gyula, Olga Ujhelly, Gyula Hadlaczky, Kobolak, Julianna, Dinnyes, Andras, Erika Csonka, Rungsiwiwut, Ruttachuk   +13 more
core   +1 more source

Interchangeability of low-dose oral contraceptives : Are current bioequivalent testing measures adequate to ensure therapeutic equivalency? [PDF]

, 1991
Current Food and Drug Administration guidelines for assessing the differences in bioavailability between generic oral contraceptives and brand-name products are inadequate to ensure therapeutic equivalence.
Ansbacher, Rudi
core   +1 more source

'No-frills prils' : GPs' views on drug costs and therapeutic interchange of angiotensin-converting enzyme inhibitors : a qualitative study

, 2021
Medications form a significant portion of spending in primary health care. Angiotensin-converting enzyme inhibitors (ACE-Is) are among the most prescribed blood pressure medications in general practice.
Lim, Hok, Webster, Susan, Wilson, Alyce, Sanci, Lena A., Lau, Phyllis (R20383)   +4 more
core   +1 more source

Comparative Analysis of Nuclear Transfer Embryo Derived Mouse Embryonic Stem Cells. Part II: Gene regulation [PDF]

, 2012
In a mouse model nuclear transfer embryo-derived embryonic stem cell lines (ntESCs) of various genetic backgrounds and donor cell types were compared with reference ESCs and analyzed comprehensively at molecular level as a second part of a larger study ...
Julianna Kobolak, Geißler, S., Mamo, S., Horsch, Marion, Horsch, M., Andras Dinnyes, Geissler, Sandra, Mamo, Solomon, Marion Horsch, Kobolak, J., Beckers, Johannes, Solomon Mamo, Kobolak, Julianna, Dinnyes, Andras, Beckers, J., Johannes Beckers, Sandra Geißler, Dinnyes, A.   +17 more
core   +1 more source

Determinação de captopril por HPLC acoplado a espectômetro de massa: aplicação em estudo de bioequivalência - doi: 10.5020/18061230.2012.p13

Revista Brasileira em Promoção da Saúde, 2012
Objetivo: Avaliar a bioequivalência de três diferentes formulações de captopril 25mg (Capoten® como formulação de referência e Captopril produzido pela FURP e Farmanguinhos como formulações testes) em 24 voluntários saudáveis de ambos os sexos.
Aline Kércia Alves Soares, Manoel Odorico de Moraes, Fernando Antônio Frota Bezerra, Gilberto de Nucci, Maria Elisabete Amaral de Moraes   +4 more
doaj   +1 more source

Evaluation of Dilution Susceptibility Testing Methods for Aztreonam in Combination with Avibactam against Enterobacterales

Microbiology Spectrum, 2022
As multidrug and pan-resistance among Enterobacterales continue to increase, there is an urgent need for more therapeutic options to treat these infections.
C. J. Kelley, A. Kennedy-Mendez, O. N. Walser, M. T. Thwaites, F. F. Arhin, C. M. Pillar, D. A. Hufnagel   +6 more
doaj   +1 more source

Full-length recombinant antibodies from Escherichia coli: production, characterization, effector function (Fc) engineering, and clinical evaluation

mAbs, 2022
Although several antibody fragments and antibody fragment-fusion proteins produced in Escherichia coli (E. coli) are approved as therapeutics for various human diseases, a full-length monoclonal or a bispecific antibody produced in E.
Md Harunur Rashid
doaj   +1 more source

Bioequivalence study of four different trademarks of enalapril maleate in spontaneously hypertensive rats Estudo da bioequivalência de quatro diferentes marcas comerciais de maleato de enalapril em ratos espontaneamente hipertensos

Acta Cirúrgica Brasileira, 2008
INTRODUCTION: High blood pressure is a systemic disease which has major clinical and psycho-social repercussions, involves a high morbidity-mortality rate and generates high costs for the health system.
Nilo César do Vale Baracho, Guilherme D'Andréa Saba Arruda, Lidinei José Alves, Márcio Felipe Salomon Carneiro, Matheus Teodoro Grilo Siqueira, Héctor Gustavo Arango, José Marcos dos Reis   +6 more
doaj   +1 more source