Results 21 to 30 of about 18,360 (297)

Using 'dead or dependent' as an outcome measure in clinical trials in Parkinson's disease [PDF]

open access: yes, 2014
Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions.Peer reviewedPublisher ...
Counsell, Carl   +4 more
core   +1 more source

The role of radiation therapy in bone metastases management [PDF]

open access: yes, 2017
Bone metastases represent an important complication of malignant tumours. Despite improvement in surgical techniques and advances in systemic therapies, management of patients with bone metastatic disease remains a powerful cornerstone for the radiation ...
DE FELICE, Francesca   +3 more
core   +1 more source

The introduction of biosimilars of low molecular weight heparins in Europe: a critical review and reappraisal endorsed by the Italian Society for Haemostasis and Thrombosis (SISET) and the Italian Society for Angiology and Vascular Medicine (SIAPAV)

open access: yesThrombosis Journal, 2017
Recently, the European Medicines Agency (EMA) authorized the introduction and marketing of Thorinane® and Inhixa®, biosimilars of the Low Molecular Weight Heparin (LMWH) enoxaparin.
Davide Imberti   +3 more
doaj   +1 more source

Treating depressive disorders with the unified protocol: A preliminary randomized evaluation. [PDF]

open access: yes, 2020
OBJECTIVES: This study aims to examine the efficacy of the Unified Protocol for Transdiagnostic Treatment of Emotional Disorders (UP) for individuals diagnosed with a depressive disorder. METHOD: Participants included 44 adults who met criteria for major
Ametaj, Amantia A.   +9 more
core   +2 more sources

Occupational (Im)mobility in the Global Care Economy: The Case of Foreign-Trained Nurses in the Canadian Context [PDF]

open access: yes, 2019
The twenty-first century has witnessed a number of significant demographic and political shifts that have resulted in a care crisis. Addressing the deficit of care provision has led many nations to actively recruit migrant care labour, often under ...
Baumann A.   +16 more
core   +2 more sources

Retroviral Replicating Vector Delivery of miR-PDL1 Inhibits Immune Checkpoint PDL1 and Enhances Immune Responses In Vitro

open access: yesMolecular Therapy: Nucleic Acids, 2017
Tumor cells express a number of immunosuppressive molecules that can suppress anti-tumor immune responses. Efficient delivery of small interfering RNAs to treat a wide range of diseases including cancers remains a challenge.
Amy H. Lin   +7 more
doaj   +1 more source

Three-Dimensional (3D) Printed Microneedles for Microencapsulated Cell Extrusion [PDF]

open access: yes, 2018
Cell-hydrogel based therapies offer great promise for wound healing. The specific aim of this study was to assess the viability of human hepatocellular carcinoma (HepG2) cells immobilized in atomized alginate capsules (3.5% (w/v) alginate, d = 225 µm ...
Bouzos, Evangelia   +6 more
core   +3 more sources

Intracerebral delivery of Carboplatin in combination with either 6 MV Photons or monoenergetic synchrotron X-rays are equally efficacious for treatment of the F98 rat glioma

open access: yesJournal of Experimental & Clinical Cancer Research, 2012
Background The purpose of the present study was to compare side-by-side the therapeutic efficacy of a 6-day infusion of carboplatin, followed by X-irradiation with either 6 MV photons or synchrotron X-rays, tuned above the K-edge of Pt, for treatment of ...
Bobyk Laure   +9 more
doaj   +1 more source

Determination of captopril by hplctandem mass spectrometry: application in a bioequivalence study [PDF]

open access: yesRevista Brasileira em Promoção da Saúde, 2012
Objective: To assess three different captopril tablet formulations of 25mg for their bioavailability (Capoten® as the reference formulation and Captopril from FURP and Farmanguinhos as the test formulations) in 24 healthy volunteers of both sexes ...
Aline Kércia Alves Soares   +4 more
doaj  

Circadian rest-activity rhythms predict cognitive function in early Parkinson's disease independently of sleep [PDF]

open access: yes, 2018
BACKGROUND: Cognitive impairment is a common and debilitating symptom of Parkinson's disease (PD), and its etiology is likely multifactorial. One candidate mechanism is circadian disruption. Although there is evidence of circadian abnormalities in PD, no
Cronin-Golomb, Alice   +4 more
core   +1 more source

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