Results 91 to 100 of about 4,893,948 (292)

MOGAD Is the Most Common Cause of Isolated Optic Neuritis in Children

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives The study aimed to characterize the clinical features, etiologies, and outcomes of isolated, first‐time pediatric ON in the post‐MOG‐IgG era. Methods This was a single‐center retrospective cohort study at Texas Children's Hospital of patients diagnosed with first‐time ON between 2018–2024, with follow‐up data collected through 2025.
Chaitanya Aduru, Akansha Chandrasekar, Kyla Blasingame, Jonathan Rosen, Jesse M. Levine, Karla Salazar, Madhuri Chilakapati, Rod Foroozan, Victoria Hardwick, Jonathan M. Yarimi, Nikita Shukla, Timothy E. Lotze, Kristen S. Fisher, Alexander J. Sandweiss   +13 more
wiley   +1 more source

The Comprehensive Live Cell‐Based Cytotoxicity Assay for Monitoring Disease Activity and Guiding Rescue Therapy in Acute Attacks of NMOSD

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Neuromyelitis optica spectrum disorder (NMOSD) is a devastating neurological disease that lacks serological biomarkers that can accurately reflect disease activity. We established a live cell‐based assay (LCBA) using serum with endogenous complement to quantify the overall cytotoxicity, offering a novel functional tool for monitoring
Xiaona Xu, Jie Ding, Yupeng Du, Guibao Luo, Jinming Li, Rui Liu, Xiaoyi Xu, Xiao Li, Minshu Li, Wei Jiang, Chunsheng Yang   +10 more
wiley   +1 more source

Therapeutic plasma exchange for the treatment of thrombotic thrombocytopenic purpura: A retrospective multicenter study

, 2007
Background: Thrombotic thrombocytopenic purpura (TTP) is a rare disease that is fatal if it is not treated.
Kabukcu, Sibel, Çıkım, Kerim, Altuntaş, Fevzi, Keskin, Ali, Kaya, Emin, SARI, İSMAİL, Ozturk, Ahmet, Kocyigit, Ismail, Cikim, Kerim, Sarı, Ismail, Eser, Bülent, Cetin, Mustafa, Unal, Ali, ERKURT, MEHMET ALİ, Erkut, M. Ali, Aydoğdu, Ismet, Cikim, K., Kabukcu, S., Altuntas, F., Kocyigit, I., Ali Erkut, M., Sari, Hakan İsmail, Aydogdu, I.   +22 more
core   +1 more source

Ofatumumab Therapy and Long‐Term Seizure Outcomes of Patients With Relapsing Anti‐NMDA Receptor Encephalitis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective There is a lack of studies on seizure outcomes associated with ofatumumab therapy in patients for relapsing anti‐N‐methyl‐D‐aspartate (NMDA) receptor encephalitis. We aimed to evaluate long‐term seizure outcomes of ofatumumab therapy for relapsing anti‐NMDA receptor encephalitis.
Jian Wang, Mengjiao Li, Ping Kong
wiley   +1 more source

Effect of therapeutic plasma exchange on amoxicillin, clindamycin, midazolam, and morphine pharmacokinetics in a critically ill child [PDF]

We report a 15-year-old boy with severe septic shock and multiple organ failure, requiring intensive care and extracorporeal therapies, including veno-arterial extracorporeal membrane oxygenation, continuous veno-venous hemodiafiltration, and therapeutic
Yaghyazaryan, André, Gracchi, Valentina; id_orcid, Kneyber, Martin C J; id_orcid, Zielhuis, Sybrand W J, Touw, Daan J; id_orcid, Mian, Paola, Schölvinck, Elisabeth H   +6 more
core   +1 more source

Effects of therapeutic plasma exchange on anticoagulants in patients receiving therapeutic anticoagulation: a systematic review.

, 2023
Therapeutic plasma exchange (TPE) removes coagulation proteins, but its impact on therapeutic anticoagulation is unknown. We performed a systematic review of the literature to determine the coagulation effects of TPE in patients receiving systemic ...
Root, Adam G, Hodulik, Kimberly L, Onwuemene, Oluwatoyosi A, Ledbetter, Leila S   +3 more
core   +1 more source

Copine‐4 Paraneoplastic Autoimmune Encephalitis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT We characterize copine‐4 (CPNE4)‐IgG and report clinical associations. Among 844 samples with unclassified neural IgGs identified by mouse‐brain indirect immunofluorescence assay over 2 years, 5 samples (serum, 3; CSF, 2) from 3 patients produced a distinctive cerebrum‐restricted synaptic pattern.
Mimi S. Fang, Amy Ml Quek, Clement Yong, Amir Adeli, Gabrielle N. Conway, Connie E. Lesnick, Diana Anissian, Divyanshu Dubey, John R. Mills, Sean J. Pittock, Anastasia Zekeridou, Michael Gilligan, Andrew McKeon   +12 more
wiley   +1 more source

Therapeutic plasma exchange for refractory SLE: A comparison of outcomes between different sub-phenotypes

, 2018
Objective: Therapeutic plasma exchange (TPE) offers an alternative therapeutic modality for patients with systemic lupus erythematosus (SLE) and primary antiphospholipid syndrome (APS).
ÖZCEBE, OSMAN İLHAMİ, Karaagac, Tulay, Bilgen, ŞAZİYE ŞULE, KARADAĞ, ÖMER, Soyuoz, Aynur, KILIÇ, LEVENT, Levent Kilic, Osman Ilhami Ozcebe, Omer Karadag, Sule Apras Bilgen, Aynur Soyuoz, Tulay Karaagac   +11 more
core   +1 more source

Efficacy of Fampridine on Refractory Optic Neuritis in Neuromyelitis Optica Spectrum Disorders

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Neuromyelitis optica spectrum disorders (NMOSD) usually occur with acute refractory optic neuritis (ON). However, there is a lack of efficacious treatments to improve recovery. Since fampridine has been found to improve the prognosis of multiple sclerosis (MS) and MS‐related ON, it is necessary to explore the efficacy of fampridine ...
Hongxuan Wang, Wanru Chen, Xiangpen Li, Hengjian Lu, Chenguang Li, Xiaoni Zhang, Lulu Bu, Xiaoyu Xu, Qingyu Shen, Ying Peng   +9 more
wiley   +1 more source

Results of the linear mixed-effects model analyzing cost (in USD) in patients with thrombotic thrombocytopenic purpura treated with therapeutic plasma exchange.

, 2021
Results of the linear mixed-effects model analyzing cost (in USD) in patients with thrombotic thrombocytopenic purpura treated with therapeutic plasma exchange.
Andry Van de Louw (9921819), Michael Darmon (282176), Elie Azoulay (20533), Eric Mariotte (4094944), Douglas Leslie (5755049), Austin Cohrs (9921822)   +5 more
core   +1 more source