Results 91 to 100 of about 1,887,170 (297)
Objective:to describe the behavior of children during the instructional session of therapeutic play (ITP) in the preoperative period and to verify the behavior presented by them during the perioperative period. Methods: Exploratory descriptive study with
Camila Moreira Paladino +2 more
doaj +1 more source
Objective: To understand, from the family’s perspective, the meaning of admitting the child in the hospital with the use of the instructional therapeutic play. Method: A phenomenological research with 12 families of children aged four to nine years old,
Bruna Ferreira Aranha +4 more
doaj +2 more sources
The role and implications of mammalian cellular circadian entrainment
At their most fundamental level, mammalian circadian rhythms occur inside every individual cell. To tell the correct time, cells must align (or ‘entrain’) their circadian rhythm to the external environment. In this review, we highlight how cells entrain to the major circadian cues of light, feeding and temperature, and the implications this has for our
Priya Crosby
wiley +1 more source
Molecular bases of circadian magnesium rhythms across eukaryotes
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley +1 more source
Understanding the dramatic therapeutic play session: a contribution to pediatric nursing
Objectives: to understand how the dramatic therapeutic play session occurs within the care of hospitalized children. Methods: qualitative multiple case study, using theoretical references, such as symbolic interactionism and Vygotsky’s theory of ...
Vera Lucia Alves dos Santos +3 more
doaj +1 more source
Immunopathogenesis of rheumatoid arthritis [PDF]
Rheumatoid arthritis (RA) is the most common inflammatory arthropathy. The majority of evidence, derived from genetics, tissue analyses, models, and clinical studies, points to an immune-mediated etiology associated with stromal tissue dysregulation that
Ahmed +115 more
core +1 more source
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
Book review: Dibs: In search of self by Virginia M. Axline
In response to James Anglin’s challenge in this journal’s previous issue, to take an old book off the shelf and reread it, I immediately thought of Virginia Axline’s Dibs: In Search of Self.
Bruce Henderson
doaj +1 more source
Play Therapy: Therapeutic Games for Children With Developmental Disabilities
Although fears and various forms of anxiety is very common and integral part of the development of every child, sometimes become so intense and prolonged that the resulting discomfort and distress to the child and his family.
Anida Dudić
doaj

