Reciprocal control of viral infection and phosphoinositide dynamics
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
Therapeutic play as a pain relief strategy for children with cancer [PDF]
Objective: To evaluate pain characteristics and alterations,demonstrated by children hospitalized with cancer, before and aftertherapeutic play. Methods: A descriptive field research using aquantitative approach conducted at the Pediatric Cancer Clinic ...
Michelle Batista de Mello Sabino +1 more
doaj
The Healing Power of Play: Therapeutic Work with Chronically Neglected and Abused Children
This article concerns a therapeutic intervention with a group of abandoned children living in a Romanian pediatric hospital. The children, ranging in age from one to ten years old, had suffered chronic neglect and abuse. They had previously spent most of
Fraser Brown
doaj +1 more source
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
Endocannabinoid-related compounds in gastrointestinal diseases [PDF]
The endocannabinoid system (ECS) is an endogenous signalling pathway involved in the control of several gastrointestinal (GI) functions at both peripheral and central levels.
Alessandra, D'Alessandro +7 more
core +1 more source
An intracellular transporter mitigates the CO2‐induced decline in iron content in Arabidopsis shoots
This study identifies a gene encoding a transmembrane protein, MIC, which contributes to the reduction of shoot Fe content observed in plants under elevated CO2. MIC is a putative Fe transporter localized to the Golgi and endosomal compartments. Its post‐translational regulation in roots may represent a potential target for improving plant nutrition ...
Timothy Mozzanino +7 more
wiley +1 more source
The Right’s Reasons: Constitutional Conflict and the Spread of Woman-Protective Anti-Abortion Argument [PDF]
The Lecture offers a provisional first account of the rise and spread of WPAA. It traces the development of gender-based antiabortion advocacy, examining the rise of post-abortion syndrome (PAS) claims in the Reagan years and the first struggles in the ...
Siegel, Reva B.
core +1 more source
Keeping company with hope and despair. Family therapists' reflections and experience of working with childhood depression [PDF]
The BIOMED international outcome study on childhood depression offered a unique opportunity for the systematic treatment of children and families with major depression using systemic psychotherapy.
Angold +11 more
core +1 more source
By dawn or dusk—how circadian timing rewrites bacterial infection outcomes
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo +2 more
wiley +1 more source
Arteterapia e Play Therapy: connessioni tra i due approcci nella psicoterapia con gli adolescenti
This article explores how key concepts of Art Therapy and Play Therapy can be compatible ways of working with adolescents. The connections between the two approaches can be identified in their philosophical structure of seeing the self as an embodied and
Tommaso Romitelli
doaj +1 more source

