Results 111 to 120 of about 18,082,299 (299)

Custo-efetividade dos análogos de nucleosídeos/nucleotídeos para hepatite crônica B Costo-efectividad de los análogos de nucleósidos/nucleótidos para hepatitis crónica B Cost-effectiveness of nucleoside/nucleotide analogues in chronic hepatitis B

Revista de Saúde Pública, 2012
OBJETIVO: Conduzir uma análise de custo-efetividade das alternativas medicamentosas com terapia de resgate na recaída por resistência viral para tratamento de pacientes com hepatite crônica B (HCB).
Alessandra Maciel Almeida, Anderson Lourenço da Silva, Cristina Mariano Ruas Brandão, Mariângela Leal Cherchiglia, Eli Iola Gurgel Andrade, Gustavo Laine Araújo de Oliveira, Ricardo Andrade Carmo, Francisco de Assis Acurcio   +7 more
doaj  

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

Therapeutic interventions: an Islamic perspective [PDF]

, 2008
Disease and its healing in most of the therapeutic strategies are mainly based either on physical or metaphysical aspects. Therapeutic strategies in Islam, on the other hand, are based on a combination of spiritual, psychological, and material means.
Shogar, Ibrahim, Rahman, Mohammad Tariqur, Bouzenita, Anke Iman, Brown, Lindsay, Nazer, Reeza   +4 more
core   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Update on Generalized Pustular Psoriasis

Acta Médica Portuguesa
Generalized pustular psoriasis (GPP) is a rare but severe inflammatory skin disease characterized by the eruption of widespread sterile pustules, often accompanied by systemic inflammation.
Tiago Torres, Joana Antunes, Rui Tavares Bello, Paulo Varela, Martinha Henrique, Gabriela Marques Pinto, Américo Figueiredo, Osvaldo Correia, Paulo Filipe, Francisco Menezes Brandão   +9 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Cannabinoids and their therapeutic use

Gaceta de M�xico, 2023
Sergio, Islas-Andrade, Luisa L, Rocha-Arrieta, Oscar, Arrieta, Miguel A, Celis, Judith, Domínguez-Cherit, Alberto, Lifshitz, Armando, Mansilla-Olivares, Iris, Martínez, Alberto José, Mimenza, Mucio, Moreno, Alejandro A, Reyes-Sánchez, Guillermo J, Ruiz-Argüelles, Antonio, Soda-Merhy, Julio, Sotelo, Sonia, Toussaint, Diana, Vilar-Compte, Emma, Verástegui   +16 more
openaire   +2 more sources

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Community-based therapeutic care: treating severe acute malnutrition in sub-Saharan Africa [PDF]

, 2009
Severe acute malnutrition (SAM) affects approximately 13 million children under-five and is associated with over 1.5 million preventable child deaths each year.
Sadler, K.
core