Results 101 to 110 of about 4,001,428 (243)

Lorlatinib‐Containing Therapy for MYCN‐Amplified, ALK‐Mutated Neuroblastoma With Bulky Leptomeningeal Relapse: A Case Report

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Central nervous system (CNS) relapse of neuroblastoma carries a poor prognosis, and craniospinal irradiation (CSI) poses substantial long‐term toxicity in young children. We report a toddler with MYCN‐amplified neuroblastoma harboring somatic ALK R1275Q who developed extensive leptomeningeal relapse with paraplegia.
Jinwoo Kim, Minji Kim, Nani Jung, Sung Eun Kim, Ji Yoon Kim, Mi Ae Chu, Jung Eun Kwon, Yeo Hyang Kim, So Mi Lee, Ki‐Su Park, Jeong Eun Lee, Ye Jee Shim   +11 more
wiley   +1 more source

SH2 Domains: Folding, Binding and Therapeutical Approaches. [PDF]

Int J Mol Sci, 2022
Diop A, Santorelli D, Malagrinò F, Nardella C, Pennacchietti V, Pagano L, Marcocci L, Pietrangeli P, Gianni S, Toto A.   +9 more
europepmc   +1 more source

Therapeutic Apheresis in Nigeria: A Multi‐Center Summary of Abstracts From the Inaugural Nigerian Society for Apheresis Scientific Meeting

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Therapeutic apheresis (TA) is an established treatment modality for hematologic, neurologic, and immunologic disorders, yet access remains severely limited in sub‐Saharan Africa. Donor apheresis, including platelet apheresis collection from healthy donors, represents an important complementary modality supporting blood product ...
Nosa Bazuaye, Chimezie Okwuonu, Evelyn Idam, Folasade Adelekan‐Popoola, Shakirat Gold‐Olufadi, Olufunto Olufela Kalejaiye, Abdullateef Ogala, Zinnah Aloziem, Blossom Amamchukwu, Patience Elimia, Mkpoikanabasi Obot‐Obot, Henry Mbakwe, Praises Maduagwuna, Olatunji Akinrodoye, Chiamaka Anyanwu, Benjamin Anyanwu, Adedamola Akinsiku, Oluwatoyin A. Akinsiku, Muzamil O. Hassan, Fatiu A. Arogundade, Olalekan E. Ojo, Homayemem Weli, Jesupelumi Adenihun, Aderemi Adelaja, Ebun Bamgboye, Olalekan Olatise, Ade E. Faponle, Ayoola Odeyemi, Michael Muoka, Stephen Asaolu, Qudrat Busari, Blessing Dawudu, Michael Naiyeju, Rasheed A. Balogun   +33 more
wiley   +1 more source

"Sweet" Hydrothorax in a Peritoneal Dialysis Patient. A Case Report and Review of the Literature on Novel Diagnostic and Therapeutical Approaches. [PDF]

Maedica (Bucur), 2023
Bucur R, Botosineanu CC, Donderski R.
europepmc   +1 more source

The Therapeutical Hemapheresis National Registry: Computerization Proposals

, 1998
The therapeutical hemapheresis National Registry, founded under the patronage of S.I.d.E., is now in its second year. It was set up to meet the need to gather experience from the various Italian groups dealing with hemapheresis and based on the former ...
E. Vitaliano, G.E. Russo, N. Leopardi
core   +1 more source

Establishing an Apheresis Medicine Program in a Resource‐Constrained Setting: A 5‐Year Experience From Lagos, Nigeria

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Establishing a comprehensive apheresis medicine program in a resource‐constrained setting presents significant structural, financial, and logistical challenges. Despite the growing clinical importance of apheresis services globally, published experience from sub‐Saharan Africa remains sparse.
Folasade Adelekan‐Popoola, Shakirat Gold‐Olufadi, Olufunto Olufela Kalejaiye, Abdullateef Ogala, Rasheed A. Balogun   +4 more
wiley   +1 more source

Comparative Evaluation of Hemodiafiltration, Hemoperfusion, and Standard Hemodialysis on Efficacy, Inflammatory Control, Dialysis Adequacy, and Safety in End‐Stage Renal Disease: A Prospective Observational Study

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Chronic micro‐inflammation in patients with end‐stage renal disease (ESRD) is a significant driver of cardiovascular complications and diminished quality of life. While standard hemodialysis (SHD) effectively manages small‐molecule clearance, its ability to remove medium‐to‐large uremic toxins—the primary catalysts of systemic ...
Hongwei Zuo, Weisi Dai, Jie Mao, Mei Ye, Xingshan Lu, Xiaocui Zhang   +5 more
wiley   +1 more source

Forecasting the Dialysis Burden in Japan: Validation‐Based Projections of Prevalence and Incidence Through 2050

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Japan has one of the highest dialysis prevalence rates worldwide and a shrinking, aging population. Whether dialysis burden has entered a sustained post‐peak phase or whether recent declines partly reflect pandemic‐related disruptions remains uncertain.
Hatice Şahin, Berrak Itır Aylı, Nüket Paksoy   +2 more
wiley   +1 more source

Fecal Serine-Protease Activity: A Pathophysiological Marker and Possible Therapeutical Target in Diarrhea-Predominant Irritable Bowel Syndrome

, 2006
Fecal Serine-Protease Activity: A Pathophysiological Marker and Possible Therapeutical Target in Diarrhea-Predominant Irritable Bowel Syndrome.
Lévêque, Mathilde, Nagy, Ferenc, Roka, Richard, Fioramonti, Jean, Lonovics, Janos, Wittmann, Tibor, Rosztoczy, Andras, Garcia Villar, Rafael, Bueno, Lionel   +8 more
core   +2 more sources

Advances in Crystallization and Precipitation Technologies for Biotherapeutics

: Modeling approaches can help develop and optimize precipitation and crystallization for a wide range of therapeutical products, such as monoclonal antibodies and Adeno-associated ...
Springs, Stacy L., Bal, Vivekananda, Barone, Paul W., Sinskey, Anthony J., Hong, Moo Sun, Trout, Bernhardt L., Braatz, Richard D., Pons Royo, Maria del Carme, Guo, Jing, Stelzer, Torsten, Myerson, Allan S.   +10 more
core   +1 more source