Results 191 to 200 of about 11,729 (255)

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

Molecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang, Hyung Seok Kim, Geum Ok Baek, Moon Gyeong Yoon, Su In Lee, Jee‐Yeong Jeong, Ji Eun Han, Soon Sun Kim, Jae Youn Cheong, Jung Woo Eun   +9 more
wiley   +1 more source

Alternative methods for pharmacological research on the action mechanisms of natural products used in the treatment of type 2 diabetes: a systematic review. [PDF]

Front Pharmacol
Espinoza-Hernández FA, Martínez-Medina S, Mata-Torres G, Cabello-Hernández CA, Andrade-Cetto A.   +4 more
europepmc   +1 more source

Translating whole‐genome doubling into precision medicine in cancer

Molecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source

CD63, a new therapeutical candidate for cholesterol homeostasis regulation through extracellular vesicles? [PDF]

Extracell Vesicles Circ Nucl Acids
Saint-Pol J, Fenart L.
europepmc   +1 more source

Longitudinal Dynamics in the Airway Bacterial Profile in Bronchiectasis. [PDF]

Open Respir Arch
Oscullo G, Gomez-Olivas JD, Martinez-García MÁ.   +2 more
europepmc   +1 more source

Citicoline and Coenzyme Q10: Therapeutic Agents for Glial Activation Reduction in Ocular Hypertension. [PDF]

Pharmaceuticals (Basel)
Matamoros JA, Rubio-Casado S, Fernández-Albarral JA, Martínez-López MA, Ramírez AI, Salobrar-García E, Marco EM, Paleo-García V, de Hoz R, López-Cuenca I, Elvira-Hurtado L, Sánchez-Puebla L, Ramírez JM, López-Gallardo M, Salazar JJ.   +14 more
europepmc   +1 more source

The Role of Nuclear Medicine in Prostate Cancer. [PDF]

Diagnostics (Basel)
Grozdic Milojevic I, Milojevic B, Skrijelj D, Bumbasirevic U, Janicic A, Kajmakovic B, Sobic-Saranovic D, Artiko V, Beatovic S.   +8 more
europepmc   +1 more source

Highlighting the molecular refinement of NSMP endometrial cancer in a case of mesonephric-like adenocarcinoma. [PDF]

Gynecol Oncol Rep
Steger K, Schnaiter S, Lax S, Bandke D, Reimer D, Marth C, Zeimet AG.   +6 more
europepmc   +1 more source