Results 121 to 130 of about 1,302,607 (412)
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2022 M. Rahman +20 more
semanticscholar +1 more source
FEBS Open Bio, EarlyView.Heterologous expression of membrane transporters in cultured cells is essential for functional characterization, but is sometimes limited by low activity. Our study compares the HDAC inhibitors butyrate, VPA and SAHA to enhance transport activity. We propose to replace butyrate by SAHA: it is equally effective, devoid of repulsive odor, costs less, and
Svenja Flögel +4 more
wiley +1 more source
The 24-h lung-function profile of once-daily tiotropium and olodaterol fixed-dose combination in chronic obstructive pulmonary disease [PDF]
, 2015 Background: This study investigated the effects on 24-h lung function and lung volume of a once-daily fixed-dose combination (FDC) of the long-acting muscarinic antagonist tiotropium and the long-acting beta(2)-agonist olodaterol in patients with chronic
Beeh, Kai-Michael +7 more
core +2 more sources
Transcranial Bipolar Direct Current Stimulation of the Frontoparietal Cortex Reduces Ketamine-Induced Oscillopathies: A Pilot Study in the Sedated Rat [PDF]
arXiv, 2020 Running title: Frontoparietal anodal tDCS reduces ketamine-induced oscillopathies.Abstract: During the prodromal phase of schizophrenia with its complex and insidious clinical picture, electroencephalographic recordings detect widespread oscillation disturbances (or oscillopathies).
arxiv
Synaptopodin is required for long-term depression at Schaffer collateral-CA1 synapses
Molecular BrainSynaptopodin (SP), an actin-associated protein found in telencephalic neurons, affects activity-dependant synaptic plasticity and dynamic changes of dendritic spines.
Yanis Inglebert +4 more
doaj +1 more source
Understanding Preclerkship Medical Students’ Poor Performance in Prescription Writing
Sultan Qaboos University Medical Journal, 2016 Objectives: This study aimed to explore reasons for poor performance in prescription writing stations of the objective structured practical examination (OSPE) and absenteeism in prescription writing sessions among preclerkship medical students at the ...
Henry James +4 more
doaj +1 more source
FEBS Open Bio, EarlyView.The tumor microenvironment is a dynamic, multifaceted complex system of interdependent cellular, biochemical, and biophysical components. Three‐dimensional in vitro models of the tumor microenvironment enable a better understanding of these interactions and their impact on cancer progression and therapeutic resistance.
Salma T. Rafik +3 more
wiley +1 more source
The pharmacology and therapeutic potential of (-)-huperzine A
Journal of Experimental Pharmacology, 2012 (-)-Huperzine A (1) is an alkaloid isolated from a Chinese club moss. Due to its potent neuroprotective activities, it has been investigated as a candidate for the treatment of neurodegenerative diseases, including Alzheimer's disease. In this review, we will discuss the pharmacology and therapeutic potential of (-)-huperzine A (1).
Maung Kyaw Moe Tun, Seth B. Herzon
openaire +5 more sources
Reslizumab in patients with inadequately controlled late-onset asthma and elevated blood eosinophils [PDF]
, 2017 INTRODUCTION: Asthma with adult onset and elevated blood eosinophils is a difficult-to-treat subgroup. This post hoc analysis evaluated reslizumab, an anti-interleukin-5 monoclonal antibody, in patients with late-onset eosinophilic asthma.
Brusselle, Guy +3 more
core +2 more sources
Hepatitis B Vaccine Nonresponse and Associated Risk Factors: Insights From a Cohort Study
Journal of Tropical MedicineHepatitis B virus (HBV) infection remains a critical global health issue, particularly in high-burden regions with substantial global morbidity and mortality.
Shuaibu Abdullahi Hudu +8 more
doaj +1 more source