What knowledge and skills are essential for specialists in Clinical Pharmacology and Therapeutics? Results of a Delphi study [PDF]
J C Mucklow
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Lymphoid and CXCR4 Cell Targeted Lipid Nanoparticles Facilitate HIV‐1 Proviral DNA Excision
Advancements in ART improve HIV‐1 patient outcomes but are unable to eliminate latent viral DNA. To address this, CXCR4‐targeted lipid nanoparticles (T‐LNPs) for delivering CRISPR‐Cas9 to excise HIV‐1 DNA in infected cells are developed. These T‐LNPs achieve ≈60% HIV‐1 DNA excision efficacy in blood and splenic tissue, demonstrating promise for ...
Sudipta Panja+6 more
wiley +1 more source
Author Correction: The role of genetic polymorphisms in the sulfation of pregnenolone by human cytosolic sulfotransferase SULT2B1a. [PDF]
Alatwi E, Bairam AF.
europepmc +1 more source
The Pharmacology and Therapeutics of Radiation [PDF]
openaire +2 more sources
Engineering of a functional protein corona with a synergistic heparin‐ATIII complex significantly improves hemocompatibility of PEG nanoparticles. Through deliberate engineering of the protein corona, a 4‐fold reduction in coagulation activation (F1 + 2) without inducing adverse thromboinflammatory reactions (CD11b, C5a) is achieved without disrupting ...
Vaidehi Londhe+5 more
wiley +1 more source
Evaluation of drug-drug interaction potentials between JP-1366 and celecoxib using physiologically based pharmacokinetic modeling. [PDF]
Choi SC, Kim J, Lim HS.
europepmc +1 more source
Subject Review: Pharmacology and Therapeutics of Anti-sense Oligodeoxynucleotides [PDF]
Waleed M. Sweileh
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A mechanically active OsteoChondral Unit (OCU)‐on‐Chip platform mimicking the OCU's functional anatomy and the strain gradient across the osteochondral interface is presented. Upon compartment‐specific hyperphysiological compression, the model replicates mechanisms observed in osteoarthritis (OA) progression, such as calcium crystal accumulation ...
Andrea Mainardi+10 more
wiley +1 more source
Editorial: Exploring small molecule probes: advancements and applications in pharmacological research. [PDF]
Yeh IJ.
europepmc +1 more source
Clinical Pharmacology & Therapeutics annual report 2004 [PDF]
C. Michael Stein
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