Results 281 to 290 of about 429,144 (355)

Potential Role of Upadacitinib in Cytomegalovirus Colitis Recurrence. [PDF]

Eur J Case Rep Intern Med
Tsujinaka K, Kanno M, Ogawa A, Kawada K, Goda M, Uehara H, Ishizawa K.   +6 more
europepmc   +1 more source

Microphysiological Systems in Cancer Research: Advancing Immunotherapy through Tumor Microenvironment‐Integrated Organ‐On‐Chip Models

Advanced Therapeutics, EarlyView.
Emerging microphysiological systems reproduce the spatial, biochemical, and cellular complexity of the tumor microenvironment, surpassing 2D cultures and murine models. By integrating patient‐derived tumors, perfusable vasculature, and immune trafficking, these organ‐on‐chip platforms reveal mechanisms of immune evasion, predict therapeutic responses ...
Fabiana Moresi, Francesco Noto, Jyothsna Vasudevan, Xavier Bisteau, Giulia Adriani, Andrea Pavesi   +5 more
wiley   +1 more source

Potentiation of paclitaxel-induced apoptosis in a non-small cell lung cancer model using the traditional Chinese drug huaier: Network pharmacology analysis, experimental verification, and clinical impact. [PDF]

Int J Clin Pharmacol Ther
Zheng W, Lai F.
europepmc   +1 more source

Rewiring Neuroimmunity: Nanoplatform Innovations for CNS Disease Therapy

Advanced Therapeutics, EarlyView.
This review explores emerging nanoplatform strategies designed to modulate neuroimmune responses for treating central nervous system (CNS) disorders. It examines structural and microenvironmental barriers, advances in multifunctional and targeted nanotechnologies, and highlights clinical progress and translational challenges, offering insights into the
Muhammad Usman Akbar, Weiwei Guo, Xin Shen, Yimeng Fang, Yilin Liu, Peng‐Yuan Wang, Roey Elnathan, Yaping Chen   +7 more
wiley   +1 more source

Expression of concern: "Caveolin-1 and Lipid Microdomains Regulate G_s Trafficking and Attenuate G_s/Adenylyl Cyclase Signaling" [Molecular Pharmacology, Volume 76, Issue 5, November 2009, Pages 1082-1093]. [PDF]

Mol Pharmacol
europepmc   +1 more source

Editorial Commitment to Trust and Integrity in Science: Implications for Pain and Anesthesiology Research. [PDF]

J Pain Res
Palermo TM, Bouhassira D, Davis KD, Hemmings Jnr HC, Hurley RW, Katz J, Pandit J, Price T, Schatman ME, Schwarz SKW, Turk D, Van de Velde M, Wiles M, Yaksh T, Yarnitsky D.   +14 more
europepmc   +1 more source

Evolution of Ocular Organ‐On‐Chip Systems for Disease Modelling and Drug Testing: Where are We Now?

Advanced Therapeutics, EarlyView.
The rise in ophthalmic diseases due to aging, screen use, and environmental factors has driven demand for better ocular models. Traditional systems fall short, encouraging the development of organ‐on‐chip devices. These microfluidic platforms replicate eye tissue architecture, enable drug screening, and simulate ocular diseases.
Sara Trujillo
wiley   +1 more source

Corrigendum: Ayahuasca-assisted meaning reconstruction therapy for grief: a non-randomized clinical trial protocol. [PDF]

Front Psychiatry
Sabucedo P, Andión O, Neimeyer RA, Soto-Angona O, Javkin J, Haro JM, Farré M, González D.   +7 more
europepmc   +1 more source

SMYD3 Promotes Immune Evasion in Clear Cell Renal Cell Carcinoma via SREBP1‐Mediated Transactivation of CD47

Advanced Science, EarlyView.
Cancer cell‐intrinsic SMYD3 orchestrates an immunosuppressive microenvironment and impairs the response to PD‐1 blockade by reprogramming immune cells landscape in the tumor microenvironment of clear cell renal cell carcinoma (ccRCC). The immunomodulatory function of SMYD3 is mediated via the SREBP1/CD47 pathway.
Zhengfang Liu, Xiumei Zhao, Maolin Zang, Huiyang Yuan, Xin Qin, Xiaofeng Li, Shuo Zhao, Ruirong Tan, Keqiang Yan, Li Liu, Yidong Fan, Ning Zhang, Benkang Shi, Bo Han, Shouzhen Chen   +14 more
wiley   +1 more source

Editorial: Are Mitochondrial Therapeutics the Next Disruptor in Molecular Healthcare? [PDF]

Mol Neurobiol
Albensi BC.
europepmc   +1 more source