Results 281 to 290 of about 1,302,607 (412)

Correction: Dysfunctional cardiac energy transduction, mitochondrial oxidative stress, oncogenic and apoptotic signaling in DiNP-induced asthma in murine model. [PDF]

Naunyn Schmiedebergs Arch Pharmacol
Kehinde SA, Olajide AT, Fatokun TP, Fouad D, Hadi NR, Elgazzar AM, James AS, Ashour MHM.   +7 more
europepmc   +1 more source

Advances in Microfluidic Cochlea‐On‐A‐Chip

Advanced Science, EarlyView.
This review systematically examines diverse cell sources for inner ear organoids and outlines stepwise induction protocols. Furthermore, it discusses current applications and prospective developments of cochlea‐on‐a‐chip technologies in areas such as deafness modeling, mechanistic studies, and drug evaluation, with particular focus on gene‐therapy drug
Tian Shen, Shanying Han, Weiwei He, Wen Yang, Xinghua Tang, Xiaolong Zhao, Xinghong Liu, Zhenhua Shao, Lin Cheng, Yu Zhao, Jiangang Fan   +10 more
wiley   +1 more source

Clinical Pharmacology: Basic Principles in Therapeutics

, 1980
C.J. Hull
openalex   +1 more source

Editorial: Targeting neuroinflammation for novel therapeutics in neurodegenerative diseases. [PDF]

Front Pharmacol
Khanal P, Chikhale R, Machhi J.
europepmc   +1 more source

Bilirubin Targeting WNK1 to Alleviate NLRP3‐Mediated Neuroinflammation

Advanced Science, EarlyView.
At physiological concentrations, bilirubin binds to the kinase domain of WNK1, thereby augmenting its activity and facilitating the phosphorylation of downstream SPAK/OSR1. This phosphorylation inhibits KCC2 activity, leading to elevate intracellular chloride levels in neurons.
Linfei Mao, Jiayu Lu, Quanjun Yang, Zhenqi Liu, Cuiping Wu, Bingbing Ke, Kaiyan Su, Haolin Yuan, Yaqi Cui, Yao Wang, Richard Salvi, Guang Yang, Shankai Yin, Feng Liu, Chunyan Li   +14 more
wiley   +1 more source

Erratum to "Morroniside Protects C2C12 Myoblasts from Oxidative Damage Caused by ROS-mediated Mitochondrial Damage and Induction of Endoplasmic Reticulum Stress" [Biomol Ther 32(3), 349-360 (2024)]. [PDF]

Biomol Ther (Seoul)
Hwangbo H, Park C, Bang E, Kim HS, Bae SJ, Kim E, Jung Y, Leem SH, Seo YR, Hong SH, Kim GY, Hyun JW, Choi YH.   +12 more
europepmc   +1 more source

Pinoresinol Diglucoside Attenuates Nuclear Receptor Coactivator 4‐Mediated Ferritinophagy Associated with Cisplatin‐Induced Hearing Loss

Advanced Science, EarlyView.
Pinoresinol diglucoside, a bioactive component extracted from traditional Chinese medicine, attenuates cisplatin‐induced ototoxicity in vivo and in vitro. The protective effect is achieved by downregulation of Socs1. The present study is the first to investigate the expression and function of Socs1 in inner ear, which is known to promote ferroptosis ...
Yin Chen, Cheng Cheng, Ao Li, Dengbin Ma, Siyu Li, Handong Wang, Song Gao, Dingding Liu, Panpan Song, Chenjie Yu, Xiaoyun Qian, Guoqiang Wan, Xia Gao   +12 more
wiley   +1 more source

Expression of concern: "Caveolin-1 and Lipid Microdomains Regulate G_s Trafficking and Attenuate G_s/Adenylyl Cyclase Signaling" [Molecular Pharmacology, Volume 76, Issue 5, November 2009, Pages 1082-1093]. [PDF]

Mol Pharmacol
europepmc   +1 more source

Corrigendum: Exploring perceived barriers and attitudes in young adults towards antidepressant pharmacotherapy, including the implementation of pharmacogenetic testing to optimize prescription practices. [PDF]

Front Pharmacol
Roberts B, Cooper Z, Landery G, Stanley S, Majda BT, Collins KRL, Akkari PA, Hood SD, Rodger J.   +8 more
europepmc   +1 more source

PATIENT BRAIN-DERIVED SOLUBLE TAU RAPIDLY AND PERSISTENTLY DISRUPTS SYNAPTIC PLASTICITY IN VIVO

IBRO Neuroscience Reports, 2023
Tomas Ondrejcak, Igor Klyubin, Neng-Wei Hu, Michael Rowan   +3 more
doaj