Results 281 to 290 of about 1,553,588 (375)

Therapeutic Conservatism

Journal of the Royal College of Physicians of London, 1993
openaire   +4 more sources

Unicorns transforming the practice of urology: value creation and allocation in the digital age. [PDF]

World J Urol
Erben P, Rodler S, Turki AT, Witzsch U, Thielscher C.   +4 more
europepmc   +1 more source

A Manual of Pharmacology and Its Application to Therapeutics and Toxicology

, 1948
NULL AUTHOR_ID
openalex   +1 more source

Lymphomatoid papulosis responding to topical methotrexate

JAAD Case Reports, 2022
Anne-Sophie Smilga, MD, Alice Dahl, MD
doaj  

The critical role of DNA damage‐inducible transcript 4 (DDIT4) in stemness character of leukemia cells and leukemia initiation

Molecular Oncology, EarlyView.
Stemness properties, including quiescence, self‐renewal, and chemoresistance, are closely associated with leukemia relapse. Here, we demonstrate that DNA damage‐inducible transcript 4 (DDIT4) is induced in the hypoxic bone marrow niche and is essential for maintaining the stemness of AML1‐ETO9a leukemia cells.
Yishuang Li, Zhijie Cao, Haiyan Xing, Zhenya Xue, Wenbing Liu, Jiayuan Chen, Yihan Mei, Runxia Gu, Hui Wei, Shaowei Qiu, Min Wang, Qing Rao, Jianxiang Wang   +12 more
wiley   +1 more source

Comment on "Adverse Impacts of PEGylated Protein Therapeutics: A Targeted Literature Review". [PDF]

BioDrugs
Goncalves J, Caliceti P.
europepmc   +1 more source

ART. XVIII.—Principles of Human Physiology, with their Chief Applications to Psychology, Pathology, Therapeutics, Hygiène, and Forensic Medicine [PDF]

William Benjamin Carpenter, Francis Gurney Smith   +1 more
openalex   +1 more source

Unveiling unique protein and phosphorylation signatures in lung adenocarcinomas with and without ALK, EGFR, and KRAS genetic alterations

Molecular Oncology, EarlyView.
Proteomic and phosphoproteomic analyses were performed on lung adenocarcinoma (LUAD) tumors with EGFR, KRAS, or EML4–ALK alterations and wild‐type cases. Distinct protein expression and phosphorylation patterns were identified, especially in EGFR‐mutated tumors. Key altered pathways included vesicle transport and RNA splicing.
Fanni Bugyi, Mirjam Balbisi, Simon Sugár, Lóránd Váncza, Eszter Regős, Ilona Kovalszky, Ibolya Laczó, Tünde Harkó, Gábor Kecskeméti, Zoltán Szabó, Judit Moldvay, László Drahos, Lilla Turiák   +12 more
wiley   +1 more source

Progress in Therapeutics [PDF]

The Boston Medical and Surgical Journal, 1902
openaire   +2 more sources

Targeting of PTP4A3 overexpression sensitises HGSOC cells towards chemotherapeutic drugs

Molecular Oncology, EarlyView.
In HGSOC with normal KRAS expression, high PTP4A3 expression regulates autophagy activation. Conversely, in HGSOC with high KRAS expression, KRAS dictates autophagy control, and PTP4A3 is not required. When high PTP4A3 expression is inhibited, HGSOC cells are preferentially sensitised towards DNA‐damaging agents.
Ana López‐Garza, David James, Emma Creagh, James T. Murray   +3 more
wiley   +1 more source