Results 301 to 310 of about 1,553,588 (375)

Practical veterinary pharmacology and therapeutics

, 1917
Howard Jay Milks
openalex   +2 more sources

Decrypting cancer's spatial code: from single cells to tissue niches

Molecular Oncology, EarlyView.
Spatial transcriptomics maps gene activity across tissues, offering powerful insights into how cancer cells are organised, switch states and interact with their surroundings. This review outlines emerging computational, artificial intelligence (AI) and geospatial approaches to define cell states, uncover tumour niches and integrate spatial data with ...
Cenk Celik, Shi Pan, Eloise Withnell, Hou Wang Lam, Maria Secrier   +4 more
wiley   +1 more source

TERN-501 monotherapy and combination therapy with TERN-101 in metabolic dysfunction-associated steatohepatitis: the randomized phase 2a DUET trial. [PDF]

Nat Med
Noureddin M, Alkhouri N, Lawitz EJ, Kowdley KV, Loomba R, Lee L, Jones C, Schlegel A, Marmon T, Anderson K, Li Y, Quirk E, Harrison SA.   +12 more
europepmc   +1 more source

Textbook of Pharmacology and Therapeutics

, 1934
NULL AUTHOR_ID
openalex   +1 more source

Microglia limit brain tumor development by restricting tumor cell proliferation and inducing T‐cell immunity

Molecular Oncology, EarlyView.
Microglia (BV2) and IL‐4‐treated BMDMs promote astrocytoma clustering and inhibit tumor growth, not shown in other macrophage cells. In vivo, microglial co‐implantation enhances CD8+ T cell infiltration, elevates Granzyme B, lowers circulating MDSCs, and extends survival only in immune‐competent mice, but not in immune‐deficient mice.
Tzu‐Chieh Sun, Ching‐Fang Yu, Sheng‐Yan Wu, Wei‐Chung Cheng, Chi‐Shiun Chiang, Fang‐Hsin Chen   +5 more
wiley   +1 more source

Advances and challenges of targeting epicardial adipose tissue (EAT) and perivascular adipose tissue (PVAT). [PDF]

Cardiovasc Diabetol
Liu D, Chen W, Guo Z, Gao Q, Wang B, Wang J, Hu W, Wang C, Wang S, Wu X, Xu M, Lan G.   +11 more
europepmc   +1 more source

The Pharmacological Basis of Therapeutics: a Textbook of Pharmacology, Toxicology and Therapeutics for Physicians and Medical Students

, 1942
NULL AUTHOR_ID
openalex   +1 more source

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

Molecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts, Senada Koljenović, Elise Daems, Karolien De Wael, Marc Peeters, Léon C. van Kempen, Greetje Vanhoutte, Karen Zwaenepoel, Timon Vandamme   +8 more
wiley   +1 more source

Randomized Phase Ib Clinical Trial of DB-020 Intratympanic Injections to Reduce High-Dose Cisplatin Ototoxicity. [PDF]

J Clin Oncol
Panizza BJ, O'Leary SJ, Hart CD, Diwakarla CS, Barnett C, Lapuerta P, Lee J, Raines S, Quigley T, Wolff HM, Keilty J, Ladwa R, Porceddu SV, McGrath M, Seetharamu N, Fua T, Rischin D.   +16 more
europepmc   +1 more source

Analysis of peripheral neuropathy in the POLARIX study using clinician- and patient-reported outcomes. [PDF]

Blood Adv
Trněný M, Fogliatto L, Gardner F, Flinn I, Larouche JF, Haioun C, Canales M, Goto H, Hajek R, Salles G, Singh A, Yan M, Kothari R, Man G, Sahin D, Hirata J, Lee C, Tilly H, Flowers CR.   +18 more
europepmc   +1 more source