Results 41 to 50 of about 2,771,868 (291)

Dog‐assisted therapy in the dental clinic: Part A—Hazards and assessment of potential risks to the health and safety of humans

Clinical and Experimental Dental Research, 2019
Background Dog‐assisted therapy in the dental clinic may be an attractive alternative to sedation for anxious patients. Including a dental therapy dog in a clinical setting introduces new hazards and potential risks to health and safety for both humans ...
Anne M. Gussgard, J. Scott Weese, Arne Hensten, Asbjørn Jokstad   +3 more
doaj   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Clifford the Big Red Dog

, 1990
Clifford the Big Red Dog is reading to ...
Bloch, Heidi
core   +2 more sources

Expression of Dog Microdystrophin in Mouse and Dog Muscles by Gene Therapy

Molecular Therapy, 2010
Duchenne muscular dystrophy (DMD) is characterized by the absence of dystrophin. Several previous studies demonstrated the feasibility of delivering microdystrophin complementary DNA (cDNA) into mouse and normal nonhuman primate muscles by ex vivo gene therapy.
Pichavant, Christophe, Chapdelaine, Pierre, Cerri, Daniel G, Dominique, Jean-Christophe, Quenneville, Simon P, Skuk, Daniel, Kornegay, Joe N, Bizario, João CS, Xiao, Xiao, Tremblay, Jacques P   +9 more
openaire   +2 more sources

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Kommt ein Hund in die Bibliothek: Neuer Lernraumservice

Bibliothek
Der Aufsatz beschreibt einen innovativen Service, der im Sommer 2022 erfolgreich an der SLUB Dresden getestet wurde. Unter dem Servicetitel „Lernpause mit Pfötchen“ wird Studierenden in der Bibliothek eine konzentrationsförderliche aktive Lernpause ...
Geissert Pauline, Ilg Jens
doaj   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

Impact of Interactions with a Puppy and Handler Versus a Handler Alone on Stress and Vitality in a University Setting: A Crossover Study

Animals
Brief interactions with a well-behaved dog can enhance wellbeing, but most campus-based dog visitation programs employ adult, trained dogs. There is little research about the impact of puppies on wellbeing or stress in this context. The aim of this study
Tiffani J. Howell, Dac L. Mai, Pam Draganovic, John-Tyler Binfet, Pauleen C. Bennett   +4 more
doaj   +1 more source

The Benefits of Dog-Assisted Therapy for Children With Anxiety

Psychotherapy and Counselling Journal of Australia, 2023
# Background Anxiety disorders are one of the most common mental health disorders experienced by children, and they have a negative effect on social, academic, and health functioning.
Andrea Wu, Ruth Wei
doaj   +1 more source