Results 91 to 100 of about 719,690 (317)

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

FEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer, Angelique Kragl, Katrin Ziems, Juliane Glaubitz, Sophie Grammbauer, Susanne Hildebrandt, Mladen V. Tzvetkov, Gabriele Jedlitschky   +7 more
wiley   +1 more source

Time‐restricted feeding prior to Mycobacterium tuberculosis infection reduces tissue CD4+ T cells with limited impact on bacterial clearance

FEBS Open Bio, EarlyView.
Time‐restricted feeding (TRF) in mice increased liver fatty acid oxidation and decreased fatty acid biosynthesis. These alterations persisted when TRF was discontinued and the host was infected with Mycobacterium tuberculosis. Pre‐exposure to TRF did not alter tissue (lung and spleen) mycobacterial burden but significantly reduced CD3+ T cells in lungs
Ashish Gupta, Nidhi Yadav, Subhasmita Das, R. Rajendra Kumar Reddy, Nupur Sharma, Amol Ratnakar Suryawanshi, Jaswinder Singh Maras, Ranjan Kumar Nanda   +7 more
wiley   +1 more source

Parameter identification of condenser heat transfer model based on improved flower pollination algorithm

Scientific Reports
Condenser heat transfer parameters serve as critical indicators for assessing the operational status of condensers. However, these parameters cannot be directly obtained through measurement or inferred solely from condenser characteristic curves, which ...
Guodong Wang, Min Zhang, Jiayu Huang, Xingchen Liu, Qichang Wang, Dekui Shen   +5 more
doaj   +1 more source

Numerical investigations of convective phenomena of oil impingement on end-windings

The Journal of Engineering, 2019
A novel experimental rig for analysing intensive liquid cooling of highly power-dense electrical machine components has been developed. Coupled fluid flow and heat transfer have been modelled, using computational fluid dynamics (CFD), to inform the ...
Peter H. Connor, Antonino La Rocca, Zeyuan Xu, Carol N. Eastwick, Stephen J. Pickering, Chris Gerada   +5 more
doaj   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

AdaHeat: A general adaptive intelligent agent for domestic heating control

, 2015
Copyright © 2015, International Foundation for Autonomous Agents and Multiagent Systems (www.ifaamas.org). All rights reserved.Improving the energy efficiency of domestic heating systems can lead to a major reduction in energy consumption and the ...
Rogers, A, Panagopoulos, Athanasios Aris, Alam, Muddasser, Jennings, NR, Jennings, N.R., Rogers, A.   +5 more
core  

Thermal analysis of induction and synchronous reluctance motors [PDF]

, 2005
In this paper, the thermal behavior of two induction motors (2.2 and 4 kW, four poles) and two synchronous reluctance motors [(SynRMs) transverse-laminated] are investigated and compared.
Staton, D., Pastorelli, Michele Angelo, A. Boglietti, D. Staton, A. Cavagnino, A. Vagati, Boglietti, Aldo, Vagati, Alfredo, Cavagnino, Andrea, STATON D., M. Pastorelli   +10 more
core   +1 more source

Comprehensive kinetic study on ammonia/ethylene counter-flow diffusion flames: influences of diluents

International Journal of Coal Science & Technology
This study aimed to investigate the effects of ammonia addition on ethylene counter-flow diffusion flames with different diluents on the fuel or oxidizer side, using kinetic analyses.
Zhimei Shu, Tingting Xu, Jiayi Xiao, Qige Deng, Xuan Zhao, Tianjiao Li, Yaoyao Ying, Dong Liu   +7 more
doaj   +1 more source

Constructing high-performance micro fuel electrodes for reversible proton ceramic electrochemical cells

Electrochemistry Communications
Reversible proton ceramic electrochemical cells (R-PCECs) are of great interest as efficient energy conversion device. Optimization of structural design can enhance the mechanical properties and gas transport of the cells, resulting in improved ...
Yeqing Ling, Feifan Huang, Bin Wang, Tao Li   +3 more
doaj   +1 more source

Hyperactive ice‐binding proteins stabilize cell membranes and improve resistance to dehydration stress in Caenorhabditis elegans

FEBS Open Bio, EarlyView.
TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose, Kotaro Ozaki, Ryohei Kuriyama, Yuka Ikemoto, Kazuhiro Mio, Yuji C. Sasaki, Tatsuya Arai, Sakae Tsuda, Yoichi Shinkai, Masahiro Kuramochi   +9 more
wiley   +1 more source