Results 31 to 40 of about 189,792 (265)

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

FEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas, Brigitta Maruzs, Zsófia E. Kálmán, Tomas Klumpler, Gyula Batta, Bálint Péterfia, Zoltán Gáspári   +6 more
wiley   +1 more source

Review of ventilation strategies to reduce the risk of disease transmission in high occupancy buildings

International Journal of Thermofluids, 2020
An unforeseen pandemic is facing the world caused by a corona virus known as SARS-CoV-2. Numerous measures are being put in place to try and reduce the spread of this deadly disease, with the most effective response to the outbreak being mass quarantines,
Tom Lipinski, Darem Ahmad, Nicolas Serey, Hussam Jouhara   +3 more
doaj   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Cooling Performance Characteristics of the Stack Thermal Management System for Fuel Cell Electric Vehicles under Actual Driving Conditions

Energies, 2016
The cooling performance of the stack radiator of a fuel cell electric vehicle was evaluated under various actual road driving conditions, such as highway and uphill travel.
Ho-Seong Lee, Choong-Won Cho, Jae-Hyeong Seo, Moo-Yeon Lee   +3 more
doaj   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

FEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Performance assessment of planar membrane dehumidifiers: Influence of flow configuration and wet-side conditions in crossflow design

Case Studies in Thermal Engineering
The present study conducts an in-depth numerical examination of heat and mass transfer attributes in a crossflow planar membrane dehumidifier, emphasizing the dehumidifier's performance under various operating conditions.
Wen-Ken Li, Shih-Pin Yang, Nien-Tsu Chou
doaj   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

Molecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena, Karin Teien Lande, Eva Diaz, Ana Vilar, Juan Cueva, Efigenia Arias, Victoria Sampayo, Alicia Abalo, Nerea González, Eva Colás, Antonio Gil‐Moreno, Miguel Abal, Gema Moreno‐Bueno, Therese Sørlie, Kristina Lindemann, Laura Muinelo‐Romay   +15 more
wiley   +1 more source

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

Molecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel, Izabela Kubiak, Lena Rutkowska, Żaneta Kasprzyk, Łukasz Kępczyński, Michał Bednarek, Dariusz Sobieraj, Jacek Wilkosz, Piotr Kania, Adam Jędrzejczyk, Bogdan Kałużewski, Agnieszka Gach, Tadeusz Kałużewski   +12 more
wiley   +1 more source

Design and Numerical Study of Induction-Heating Graphitization Furnace Based on Graphene Coils

Applied Sciences
Induction-heating graphitization furnaces are widely used to produce high-purity graphite products due to their high heating rate, high-limit temperatures, safety, cleanliness, and precise control. However, the existing induction-heating systems based on
Rui Li, Yuanyuan Zhang, Xiaodong Chu, Lin Gan, Jia Li, Baohua Li, Hongda Du   +6 more
doaj   +1 more source

Cold plasma processing of sesame milk: Changes on physicochemical properties, nutrition, anti-nutritional factors, protein structure and allergenicity

Applied Food Research, 2023
In the recent decade, consumers have preferred plant-based (vegan) foods due to the maintenance of environmental sustainability. However, some of the plant-based foods have a demerit of the presence of anti-nutritional factors and allergenic components ...
M. Dharini, R. Anbarasan, S. Jaspin, R. Mahendran   +3 more
doaj   +1 more source