Results 31 to 40 of about 175,078 (265)

Phosphoinositides and inositol phosphates as molecular glues

open access: yesFEBS Letters, EarlyView.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry   +9 more
wiley   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

open access: yesFEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

Simulation-Based RF-ICP Torch Optimization for Efficient and Environmentally Sustainable Radioactive Waste Management

open access: yesRecycling
This study examines methods to improve the energy efficiency of radiofrequency inductively coupled plasma (RF-ICP) torches for radioactive waste treatment, with a focus on surpassing the typical energy efficiency limit of approximately 70%.
Roman Stetsiuk   +2 more
doaj   +1 more source

Effects of Buffer Gases on Graphene Flakes Synthesis in Thermal Plasma Process at Atmospheric Pressure

open access: yesNanomaterials, 2020
A thermal plasma process at atmospheric pressure is an attractive method for continuous synthesis of graphene flakes. In this paper, a magnetically rotating arc plasma system is employed to investigate the effects of buffer gases on graphene flakes ...
Cheng Wang   +5 more
doaj   +1 more source

Application of non-thermal plasma in medicine: a bibliometric and visualization analysis

open access: yesFrontiers in Physics, 2023
Non-thermal plasma has been widely studied in medicine due to its beneficial effect with low thermal or other damages. Numerous medical research studies have been conducted using non-thermal plasma devices; yet, to date, there is no report summarizing ...
Linna Guo   +7 more
doaj   +1 more source

The diagnostics of thermal plasmas [PDF]

open access: yesPure and Applied Chemistry, 1992
Abstract
Schram, D.C.   +2 more
openaire   +2 more sources

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

Recent trends in non-thermal plasma and plasma activated water: Effect on quality attributes, mechanism of interaction and potential application in food & agriculture

open access: yesFood Chemistry Advances, 2023
The awareness of this era in consuming safe, nutritional, and minimally processed food is growing continuously. In order to address all of these consumer expectations, the food industry has adopted innovative non-thermal processes.
Sunil Pipliya   +3 more
doaj   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

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