Results 31 to 40 of about 338,421 (267)
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Journal of Dairy Science: Thermoduric bacteria, defined as those that survive temperatures considerably above their maximum growth temperature, are enumerated in milk using the laboratory pasteurization count (LPC) test.
Caroline Motzer +2 more
doaj +1 more source
Selected Problems of Power MOSFETs Thermal Parameters Measurements
Energies, 2021 In the paper, selected problems that are related to the measurements of thermal parameters of power MOSFETs that are placed on a common heat sink are analysed.
Krzysztof Górecki +1 more
doaj +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Research of heat conductivity of quartz material
Қарағанды университетінің хабаршысы. Физика сериясыIn the article the results of a study of heat conductivity and thermal resistance of quartz-containing materials were presented. The object of the study was a quartz mineral from the Aktas deposit, located in the Ulytau district of the Karaganda region.
A.K. Хасенов +6 more
doaj +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
FEBS Letters, EarlyView.Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante +10 more
wiley +1 more source
Journal of Natural Fibers, 2022 Elastic weft knitted single jersey fabrics are produced by plating of elastane (elastomeric polyurethane) yarn with lyocell yarn in a circular knitting machine with positive feeder.
P C Shobanasree +3 more
doaj +1 more source
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
FEBS Letters, EarlyView.Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
Heat Transfer Performance Analysis on the CO2 Two-phase Thermosyphon Loop
Zhileng xuebao, 2016 In terms of environmental conservation, it is very meaningful to use CO2 as working fluid in the two-phase thermosyphon loop (TPTL) to replace R22. According to the experimental results in some research, the flow boiling or condensation heat transfer ...
Tong Zhen +3 more
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