Results 61 to 70 of about 402,137 (316)

Single-Loop Triple-Diameter Pulsating Heat Pipes at Reduced Heat Input: A CFD Study on Inner Diameter Optimization

Energies
The geometric configuration, particularly the inner tube diameter, plays a significant role in the thermal performance of pulsating heat pipes (PHPs).
Rasoul Fallahzadeh, Masoud Hatami Garousi, Luca Pagliarini, Fabio Bozzoli, Luca Cattani   +4 more
doaj   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Thermal Impacts of Air Cavities Associated with Insulated Panels Deployed for Exterior Building Envelope Assemblies

Energies
This paper presents a comprehensive investigation to evaluate the impacts of air cavities between existing walls and insulated panels on the overall R-values of the retrofitted building envelope systems, addressing a key challenge in exterior envelope ...
Utsav Dahal, Moncef Krarti
doaj   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

Molecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov, Shiva Krishna Katkam, Zhefan Wang, Venkateshwar G. Keshamouni   +3 more
wiley   +1 more source

Utilization of temperature kinetics as a method to predict treatment intensity and corresponding treated wood quality : durability and mechanical properties of thermally modified wood [PDF]

, 2014
Wood heat treatment is an attractive alternative to improve decay resistance of wood species with low natural durability. However, this improvement of durability is realized at the expense of the mechanical resistance.
GERARDIN, Phillipe, Hannouz,S, Gérardin,P, Gérardin, P., Dumarçay,S, Pétrissans, M., Collet,R, Pétrissans,M, Dumarçay, S., Pétrissans, A., Pétrissans,A, Elaieb, Mohamed Tahar, HANNOUZ, Simon, Candelier,K, PETRISSANS, Mathieu, Collet, R., Hannouz, S., Elaieb,M, Candelier, K., ELAIEB, Mohamed, CANDELIER, Kévin, PETRISSANS, Anelie, DUMARÇAY, Stéphane, Gérardin, Philippe, Elaieb, M., COLLET, Robert   +25 more
core   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

Molecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena, Karin Teien Lande, Eva Diaz, Ana Vilar, Juan Cueva, Efigenia Arias, Victoria Sampayo, Alicia Abalo, Nerea González, Eva Colás, Antonio Gil‐Moreno, Miguel Abal, Gema Moreno‐Bueno, Therese Sørlie, Kristina Lindemann, Laura Muinelo‐Romay   +15 more
wiley   +1 more source

Experimental studies of thermal resistance in a vapor chamber heat spreader

, 2013
In recent years, with the increasing heat dissipation of electrical appliances, efficient cooling systems are required to solve the elevated temperature problems encountered in certain interior areas of electrical devices.
Kang, Shung-Wen, Tsai, Meng-Chang; Kang, Shung-wen; Kleber Vieira de Paiva   +1 more
core   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

thermal resistance

, 2014
Citation: 'thermal resistance' in the IUPAC Compendium of Chemical Terminology, 3rd ed.; International Union of Pure and Applied Chemistry; 2006. Online version 3.0.1, 2019. 10.1351/goldbook.T06308 • License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International for individual terms.
openaire   +1 more source