Results 51 to 60 of about 4,567,939 (306)

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

A Numerical Investigation on Hydrothermal Performance of Micro Channel Heat Sink with Periodic Spatial Modification on Sidewalls

open access: yesMicromachines, 2022
Electronic gadgets have been designed to incorporating very small components such as microcontrollers, electronic chips, transistors, microprocessors, etc. These components are exceptionally heat sensitive and can be wrecked if heat is not released. As a
Nikita Kumari   +8 more
doaj   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

Degradation processes in LED modules

open access: yesSemiconductor Physics, Quantum Electronics & Optoelectronics, 2016
Electrical-heat-light degradation model of a light-emitting module has been developed in this work. The Monte-Carlo method was used to calculate the reliability time of LED modules with different halfwidth of LED chip series resistance. Separation of LED
V.M. Sorokin
doaj   +1 more source

Building and Architectural Details of Tenement Houses Built at the Turn of the 19th and 20th Centuries in Central European Region—Hygrothermal Analysis

open access: yesBuildings, 2023
Restoring historic buildings is a challenging task in an environment where any insensitive or unprofessional intervention can cause irreparable damage. Among the most important demands currently placed on the construction industry are the protection of ...
Klara Kroftova, Radek Zigler
doaj   +1 more source

Thermal Conductivity of Carbon Nanotubes and their Polymer Nanocomposites: A Review [PDF]

open access: yes, 2011
Thermally conductive polymer composites offer new possibilities for replacing metal parts in several applications, including power electronics, electric motors and generators, heat exchangers, etc., thanks to the polymer advantages such as light weight ...
Fina, Alberto   +3 more
core   +1 more source

Tunable thermal rectification and negative differential thermal resistance in gas-filled nanostructure with mechanically-controllable nanopillars

open access: yes, 2022
Click on the DOI to access this article (may not be free).In this study, by using the nonequilibrium molecular dynamics and the kinetic theory, we examine the tailored nanoscale thermal transport via a gas-filled nanogap structure with mechanically ...
Li, Fan   +9 more
core   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

Heat Resistance in Liquids of Enterococcus spp., Listeria spp., Escherichia coli, Yersinia enterocolitica, Salmonella spp. and Campylobacter spp

open access: yesActa Veterinaria Scandinavica, 2003
The aim of the work was to collect, evaluate, summarize and compare heat resistance data reported for Campylobacter, Enterococcus, Escherichia, Listeria, Salmonella and Yersinia spp.
Sörqvist S
doaj   +1 more source

Pile heat exchangers: thermal behaviour and interactions [PDF]

open access: yes, 2013
Thermal piles – that is structural foundation piles also used as heat exchangers as part of a ground energy system – are increasingly being adopted for their contribution to more sustainable energy strategies for new buildings.
Loveridge, F.A.   +3 more
core   +1 more source

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