Results 71 to 80 of about 27,205 (257)
Optimizing photoexcitation conditions for time‐resolved X‐ray solution scattering experiments
Time‐resolved X‐ray solution scattering (TR‐XSS) is a powerful technique to visualize how proteins change their structure in real time after light activation. Selecting the right laser photoexcitation conditions—fluence, excitation geometry, and sample refresh rate—is critical to maximize the experimental signal while avoiding unwanted side effects ...
Matteo Levantino
wiley +1 more source
Thermal sensation and thermal comfort in changing environments
It is the purpose of this study to investigate thermal sensation (TS) and thermal comfort (TC) in changing environments. Therefore, 10 subjects stayed in a 30 °C, 50% relative humidity for 30 min in summer clothes and then moved to a 20 °C room where they remained seated for 30 min (Hot to Reference - HR). Similarly, 11 subjects moved from a 10 °C, 50%
Velt, K.B., Daanen, H.A.M.
openaire +3 more sources
GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain +11 more
wiley +1 more source
Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley +1 more source
Global warming and accelerated urbanization have exposed urban residents to more severe threats of heat waves and extreme high temperatures. During daily commuting, people are inevitably exposed to solar radiation environments, enduring prolonged direct ...
Xin Wu +7 more
doaj +1 more source
Systemic sclerosis (SSc) is a rare autoimmune disease defined by immune dysregulation, vasculopathy, and progressive fibrosis of the skin and internal organs. Despite advances in care, major complications such as interstitial lung disease (ILD) and myocardial involvement remain the leading causes of morbidity and mortality.
Cristiana Sieiro Santos +2 more
wiley +1 more source
On Thermal Sensation and Entropy
A neurophysiological thesis is proposed for thermal sensitivity that accounts for the disorder in physical processes that is fundamental to temperature. There is likely some form of thermal equilibrium rapidly established between thermoreceptors and the external environment local to those thermoreceptors that accounts for gauging the temperature ...
openaire +3 more sources
Effect on human metabolic rate of skin temperature in an office occupant
The motivation of this study is to get a better understanding about the real thermal sensation of people in an office environment who undertakes moderate activities.
Abu Bakar Rosli +3 more
doaj +1 more source
Driving comfort and driving safety are essential factors for drivers. As the environment of vehicle affects the comfort sensation and the arousal level of the drivers, it is necessary to contemplate the way to design of environmental factors inside ...
Jongseong Gwak +2 more
doaj +1 more source
Objective Although the definition of a gout flare is well established, the state of gout flare resolution has not yet been defined. This study aimed to explore patients’ experiences and perceptions of gout flare resolution. Methods Semistructured interviews were conducted with 24 people with gout, guided by open‐ended questions exploring their ...
Sarah Stewart +5 more
wiley +1 more source

