Results 81 to 90 of about 1,944,595 (287)

ASSESSMENT OF THERMAL SENSATION OF RESIDENTS IN THE SOUTHERN GREAT PLAIN, HUNGARY [PDF]

open access: yesAerul şi Apa: Componente ale Mediului, 2014
This study examines the subjective thermal sensation characteristics of people living in Szeged, in the Southern Hungarian Great Plain. Micrometeorological measurements were conducted with two mobile stations in six urban public spaces during 70 days ...
KOVÁCS A.   +2 more
doaj  

TRPV1‐lineage neurons are required for thermal sensation [PDF]

open access: yesThe EMBO Journal, 2010
The ion-channel TRPV1 is believed to be a major sensor of noxious heat, but surprisingly animals lacking TRPV1 still display marked responses to elevated temperature. In this study, we explored the role of TRPV1-expressing neurons in somatosensation by generating mice wherein this lineage of cells was selectively labelled or ablated. Our data show that
Santosh K, Mishra   +4 more
openaire   +2 more sources

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

open access: yesFEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain   +11 more
wiley   +1 more source

Thermal sensations of secondary schoolchildren in summer [PDF]

open access: yesJournal of Hygiene, 1973
SUMMARYSummer thermal sensations of secondary schoolchildren in England are compared with those earlier published for winter. Heat stress, contrary to expectation, is seen to decrease during the warm months, and neutrality is found to increase by some 6° F.
openaire   +4 more sources

The C‐terminal domain of yeast Arginyltransferase1 is essential for its catalytic activity

open access: yesFEBS Open Bio, EarlyView.
Arginyltransferase 1 (Ate1), a eukaryotic enzyme, catalyses arginylation, transferring arginine from tRNA‐Arg to the amino terminus of the target protein. Overexpression of Ate1 in yeast is lethal and is dependent on arginylation. This study elucidates how mutations in the cofactor‐binding and active site of Ate1 and truncation of its structural ...
Vikas Kumar Yadav   +4 more
wiley   +1 more source

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

open access: yesAging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

Experimental study on overall and local thermal comfort under different radiation intensities [PDF]

open access: yesE3S Web of Conferences
Shortwave radiation constitutes the principal source of thermal loading within automobile cabins, exhibiting characteristics of transient change and non-uniform distribution.
Zeng Yingqi   +3 more
doaj   +1 more source

Artificial Intelligence in Systemic Sclerosis: Clinical Applications, Challenges, and Future Directions

open access: yesArthritis Care &Research, EarlyView.
Systemic sclerosis (SSc) is a rare autoimmune disease defined by immune dysregulation, vasculopathy, and progressive fibrosis of the skin and internal organs. Despite advances in care, major complications such as interstitial lung disease (ILD) and myocardial involvement remain the leading causes of morbidity and mortality.
Cristiana Sieiro Santos   +2 more
wiley   +1 more source

Models and Indicators to Assess Thermal Sensation Under Steady-state and Transient Conditions

open access: yesEnergies, 2019
The assessment of thermal sensation is the first stage of many studies aimed at addressing thermal comfort and at establishing the related criteria used in indoor and outdoor environments. The study of thermal sensation requires suitable modelling of the
Diana Enescu
doaj   +1 more source

A Return to Normality: A Descriptive Qualitative Interview Study Exploring the Patient Experience of Gout Flare Resolution

open access: yesArthritis Care &Research, EarlyView.
Objective Although the definition of a gout flare is well established, the state of gout flare resolution has not yet been defined. This study aimed to explore patients’ experiences and perceptions of gout flare resolution. Methods Semistructured interviews were conducted with 24 people with gout, guided by open‐ended questions exploring their ...
Sarah Stewart   +5 more
wiley   +1 more source

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