Results 51 to 60 of about 1,944,595 (287)
FEBS Letters, EarlyView.Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
Students' perception towards thermal sensation in libraries / Chen Sin Yee [PDF]
, 2015 Recently, the effect of thermal sensation found to greatly impacted on the outcome or productivity of work within an area. Based on the thermal environment data, the air temperature and mean radiant temperature found to be in compliance with the standard
Chen, Sin Yee
core
, 2019 Previous studies have demonstrated that non-thermal factors may affect occupants' thermal response in the indoor environment. The effects of demographic and contextual factors on thermal perception have been extensively studied, yet in previous studies ...
Zhang, Fan, de Dear, Richard
core +1 more source
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Thermal comfort conditions in airport terminals: Indoor or transition spaces? [PDF]
, 2016 This paper reports on the investigation of the thermal comfort conditions in three airport terminals in the UK. In the course of seasonal field surveys, the indoor environmental conditions were monitored in different terminal areas and questionnaire ...
Kotopouleas, Alkis +1 more
core +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
A Thermal Comfort Evaluation Model for Contact Heat Transfer Based on Thermophysiology [PDF]
E3S Web of ConferencesThis study integrates the Joint System Thermoregulation Model (JOS) with four different thermal sensation models to establish a thermophysiological-thermal sensation computational framework capable of handling complex contact heat transfer scenarios. The
Song Linye +4 more
doaj +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Thermal comfort based fuzzy logic control [PDF]
, 2001 Most heating, ventilation and air conditioning (HVAC) control systems are considered as temperature control problems. In this work, the predicted mean vote (PMV) is used to control the indoor temperature of a space by setting it at a point where the PMV ...
Underwood, Chris +2 more
core +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source