Results 71 to 80 of about 1,944,595 (287)
Molecular Oncology, EarlyView.The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington +10 more
wiley +1 more source
Desenvolvimento e Meio Ambiente, 2019 Prediction models of thermal comfort in open spaces are considered a fundamental tool in neighborhood planning, as well as in open space design within urban areas. However, most of these indices were developed for cold climates.
Mirna Milena Aquino +2 more
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Journal of Asian Architecture and Building Engineering, 2023 Sensory experience is vital in creating a local identity in historical buildings and should ideally be conserved along with basic spatial structure. Hence, this study explores the relation between the spatial structure and thermal sensation experience by
Xing Chen +4 more
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The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer
Molecular Oncology, EarlyView.Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad +2 more
wiley +1 more source
Thermal sensation and thermal comfort in changing environments
Journal of Building Engineering, 2017 It is the purpose of this study to investigate thermal sensation (TS) and thermal comfort (TC) in changing environments. Therefore, 10 subjects stayed in a 30 °C, 50% relative humidity for 30 min in summer clothes and then moved to a 20 °C room where they remained seated for 30 min (Hot to Reference - HR). Similarly, 11 subjects moved from a 10 °C, 50%
Velt, K.B., Daanen, H.A.M.
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FEBS Open Bio, EarlyView.UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová +2 more
wiley +1 more source
The intensive summation of thermal sensations. [PDF]
Psychological Monographs, 1921 n ...
Baron, Annette, Bentley, Madison
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Evaluation of thermal and vibration sensation in diabetic neuropathy [PDF]
Diabetologia, 1985 Sensory evaluation of diabetic neuropathy was undertaken by a new technique for assessment of thermal sensitivity. The method is simple and reproducible, and the mean normal value of the lateral border of the foot was 6.0 degrees C (3.6-9.8 degrees C, 95% confidence limits).
R J, Guy +3 more
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Effect of terahertz irradiation on DNA damage repair in living cells
FEBS Open Bio, EarlyView.We investigated the effect of terahertz (THz) wave irradiation on DNA double‐strand break (DSB) repair in living cells. We found that THz irradiation enhanced DSB repair at specific frequencies, whereas heat treatment inhibited it, indicating that this effect is nonthermal and frequency‐specific.
Yuya Ueno +3 more
wiley +1 more source
Thermal sensation of children and its predictive evaluation method in Indonesia’s dry season
Journal of Asian Architecture and Building EngineeringThere is a discrepancy between children’s thermal sensation in hot-humid climates near the equator and conventional thermal comfort indexes, such as the predicted mean vote (PMV).
Masaya Kitaura +3 more
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