Results 71 to 80 of about 2,092,491 (287)

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

FEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain, Elise Buret, Le Hoang Thanh Nguyen, Marion Cocheteux, Nicolas Touya, Mélanie Dhayer, Romain Dubois, Frank Lafont, Sebastien Janel, Patrice Maboudou, Steve Lancel, Philippe Marchetti   +11 more
wiley   +1 more source

Challenging the assumptions for thermal sensation scales [PDF]

, 2016
Scales are widely used to assess the personal experience of thermal conditions in built environments. Most commonly, thermal sensation is assessed, mainly to determine whether a particular thermal condition is comfortable for individuals.
Fuchs, Xaver, Dovjak, Mateja, Hawighorst, Maren, Kolarik, Jakub, Fuchs, Xaver ; https://orcid.org/, Schweiker, Marcel, Becker, Susanne, Shukuya, Masanori, Maren Hawighorst   +8 more
core   +1 more source

The C‐terminal domain of yeast Arginyltransferase1 is essential for its catalytic activity

FEBS Open Bio, EarlyView.
Arginyltransferase 1 (Ate1), a eukaryotic enzyme, catalyses arginylation, transferring arginine from tRNA‐Arg to the amino terminus of the target protein. Overexpression of Ate1 in yeast is lethal and is dependent on arginylation. This study elucidates how mutations in the cofactor‐binding and active site of Ate1 and truncation of its structural ...
Vikas Kumar Yadav, Shweta Shweta, Manisha Malhotra, Vikash Maurya, Akhilesh Kumar   +4 more
wiley   +1 more source

Selective elimination of quiescent cancer cells by dequalinium chloride via ROS‐mediated ferroptosis

FEBS Open Bio, EarlyView.
Dequalinium chloride (DQ) selectively eliminates quiescent cancer cells (QCCs) by amplifying mitochondrial ROS. QCCs exhibit elevated basal ROS and limited redox‐buffering capacity, making them vulnerable to further ROS increases. DQ‐induced ROS exceeds the tolerance threshold, triggering lipid peroxidation and ferroptosis, whereas proliferating cells ...
Kotaro Miyamoto, Shiori Sakai, Minori Endo, Terigele, Mizuho Niibori, Taiki Morita, Yu Goto, Arisa Yoshida, Tomohiro Tanaka, Ning Lin, Takahiro Kuchimaru, Hiroyuki Nakamura, Masahiro Inoue, Shinae Kizaka‐Kondoh, Tetsuya Kadonosono   +14 more
wiley   +1 more source

Thermal sensation and thermal comfort in changing environments

Journal of Building Engineering, 2017
It is the purpose of this study to investigate thermal sensation (TS) and thermal comfort (TC) in changing environments. Therefore, 10 subjects stayed in a 30 °C, 50% relative humidity for 30 min in summer clothes and then moved to a 20 °C room where they remained seated for 30 min (Hot to Reference - HR). Similarly, 11 subjects moved from a 10 °C, 50%
Velt, K.B., Daanen, H.A.M.
openaire   +3 more sources

The relation between thermal sensation and skin temperature.

, 2014
The vertical axis is TSV(thermal sensation vote), and the horizontal axis is mean skin temperature (°C). This figure shows the relation between thermal sensation and mean skin temperature in the transient process from cool to neutral (square label) and ...
Baizhan Li (450520), Kechao Xia (618230), Dong Yang (141041), Zhichao Huang (316851), Wei Yu (43094), Xiuyuan Du (618228), Hong Liu (50694), Jianke Liao (618229)   +7 more
core   +1 more source

Ultrafast visual detection of Streptococcus suis via HtpsC‐targeted LAMP–CRISPR–Cas12a coupled with lateral flow immunochromatography

FEBS Open Bio, EarlyView.
A rapid visual test combines DNA amplification, CRISPR–based target verification, and a lateral flow strip to detect Streptococcus suis. The assay gives results in about 45 min, reduces false‐positive interpretation, and does not require fluorescence equipment.
Liu‐xin Li, Miao Xin, Xiao‐wen Cui, Shi‐yin Yu, Fei Meng, Min Cao, Xiao‐hui Xiong, Yi‐chen Lu   +7 more
wiley   +1 more source

Effects of solar radiation on human thermal comfort under different activity intensities —— a chamber study

Journal of Asian Architecture and Building Engineering
Global warming and accelerated urbanization have exposed urban residents to more severe threats of heat waves and extreme high temperatures. During daily commuting, people are inevitably exposed to solar radiation environments, enduring prolonged direct ...
Xin Wu, Aimei Luo, Chaopu Yuan, Xiaofang Lu, Meng Zhen, Yu Shao, Qi Dong, Guangmeng Bian   +7 more
doaj   +1 more source

Experimental study on overall and local thermal comfort under different radiation intensities [PDF]

E3S Web of Conferences
Shortwave radiation constitutes the principal source of thermal loading within automobile cabins, exhibiting characteristics of transient change and non-uniform distribution.
Zeng Yingqi, Zhou Xiang, Zhai Yongchao, Xia Haifeng   +3 more
doaj   +1 more source

Fluorination: A strategy to tune the interactions of molecules and nanoscale systems with biological matter

FEBS Open Bio, EarlyView.
This minireview explores fluorination as a key strategy to optimize therapeutic molecules and nanocarriers. By incorporating different fluorinated motifs—from single atoms to linear and branched chains—drug delivery, cellular uptake, and colloidal stability can be improved and fine‐tuned.
Martina Beccalli, Beatrice Lucia Bona, Francesca Baldelli Bombelli   +2 more
wiley   +1 more source