Results 41 to 50 of about 2,576,925 (290)

Waterless virtual footbath using airflow and thermal contrast: design and exploratory evaluation of relaxation-oriented VR experience

Frontiers in Virtual Reality
Conventional footbaths promote relaxation but require water management and hygiene control, limiting portability and reproducibility. We propose a waterless virtual footbath system that reproduces immersion-like sensations using airflow-based tactile ...
Zi Xin, Hiroaki Yano, Kazuhiro Fujitsuka, Tomohiro Amemiya, Vibol Yem, Vibol Yem   +5 more
doaj   +1 more source

Experimental Simulation of the Exploitation of Natural Gas Hydrate

Energies, 2012
Natural gas hydrates are cage-like crystalline compounds in which a large amount of methane is trapped within a crystal structure of water, forming solids at low temperature and high pressure.
Chang-Yu Sun, Guang-Jin Chen, Ben-Cheng Wu, Xin Yang, Ke-Hua Su, Qing Yuan, Bei Liu   +6 more
doaj   +1 more source

Involvement of ERK phosphorylation of trigeminal spinal subnucleus caudalis neurons in thermal hypersensitivity in rats with infraorbital nerve injury. [PDF]

PLoS ONE, 2013
To evaluate the involvement of the mitogen-activated protein kinase (MAPK) cascade in orofacial neuropathic pain mechanisms, this study assessed nocifensive behavior evoked by mechanical or thermal stimulation of the whisker pad skin, phosphorylation of ...
Ikuko Suzuki, Yoshiyuki Tsuboi, Masamichi Shinoda, Kazuo Shibuta, Kuniya Honda, Ayano Katagiri, Masaaki Kiyomoto, Barry J Sessle, Shingo Matsuura, Kinuyo Ohara, Kentaro Urata, Koichi Iwata   +11 more
doaj   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Development Efficiency Assessment of Challenging Hydrates Under Reservoir Fracturing and Thermal Stimulation Using an XGBoost-SHAP Framework

Journal of Marine Science and Engineering
Reservoir fracturing combined with thermal stimulation is a highly promising strategy for the development of challenging hydrates. However, the synergistic influence mechanisms of multiple engineering parameters on productivity remain poorly understood ...
Honghong Li, Lihui Zheng, Shuaishuai Nie, Xiuping Zhong, Qin Guo, Maozong Gan, Ke Liu   +6 more
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Functional MRI with active, fully implanted, deep brain stimulation systems: Safety and experimental confounds [PDF]

, 2007
We investigated safety issues and potential experimental confounds when performing functional magnetic resonance imaging (fMRI) investigations in human subjects with fully implanted, active, deep brain stimulation (DBS) systems.
Lemieux, L., Thornton, John, Yousry, Tarek, Thobois, S., Pinto, Serge, Allen, P.J., Lemieux, Louis, Carmichael, David, Limousin-Dowsey, Patricia, Pinto, S., Limousin-Dowsey, P., Thornton, J.S., Thobois, Stéphane, Carmichael, D.W., Yousry, T., Allen, Philip   +15 more
core  

Artificial molecular machines and motors—Design and control of nanoscale motion

FEBS Letters, EarlyView.
Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley   +1 more source

Techno-Economic Assessment of Fracturing-Assisted Thermal Stimulation for Gas Hydrate Extraction: Field-Scale Numerical Simulation and Net Present Value Analysis

Energies
Horizontal well fracturing and thermal injection co-stimulation is widely regarded as a key technology for enhancing the development potential of gas hydrates in the Shenhu Area of the South China Sea, yet its economic feasibility has not been ...
Ke Liu, Shuaishuai Nie, Xiuping Zhong, Youqin Feng, Dongbin Pan   +4 more
doaj   +1 more source