Results 181 to 190 of about 21,084 (341)

Conformable Microelectrode Arrays Integrated with a Scoop‐Shaped Slide‐Well for Dynamic Electrophysiological Profiling of Patient‐Derived Cardiac Organoids

open access: yesAdvanced Science, EarlyView.
A flexible, ultrathin multi‐channel microelectrode array (MEA) conformally integrated onto a curved slide‐well enables stable electrical interfacing with 3D cardiac organoids. The geometry‐guided self‐alignment allows simultaneous recording of extracellular field potentials and contractile motion from irregular, beating tissues.
Ye Seul Kim   +12 more
wiley   +1 more source

Targeting the PDK1/c‐Myc/SOX10 Signaling in Oligodendrocytes Alleviates Neuropathic Pain

open access: yesAdvanced Science, EarlyView.
This work reveals that oligodendrocyte homeostasis, mediated by PDK1, is a critical determinant of neuropathic pain (NPP) pathogenesis. Disruption of PDK1 in oligodendrocytes impairs SOX10‐dependent myelination programs through c‐Myc accumulation, leading to disrupted myelination and the pathophysiology of NPP.
Pingping Qiao   +7 more
wiley   +1 more source

PET Imaging of Cardiac Inflammation in Viral Myocarditis Using a DPP4‐Targeted Probe

open access: yesAdvanced Science, EarlyView.
This study describes a DPP4‐targeted PET probe for imaging myocardial inflammation by selectively targeting activated immune cells. Derived from the clinically approved small‐molecule inhibitor linagliptin, the probe demonstrates favorable biodistribution with specific cardiac uptake in myocarditis.
Wanhao Gao   +14 more
wiley   +1 more source

Feature issue introduction: persistent and photostimulable phosphors: an established research field with clear challenges ahead [PDF]

open access: yes, 2016
Chen, Wei   +5 more
core   +1 more source

Thermally Degradable Biocompatible Hydrogel as Transient Encapsulation Coating for Implantable Sensors

open access: yesAdvanced Science, EarlyView.
A biocompatible hydrogel coating with tissue‐like mechanics and reversible dissolution triggered by a mild, physiologically compatible temperature drop (≈37°C → ≈25°C) was developed for the transient encapsulation of implantable devices. The physically crosslinked methylcellulose, polyethylene glycol and polyacrilic acid (MC/PEG/PAA) hydrogel ...
Francesca Persano   +14 more
wiley   +1 more source

Three model space experiments on chemical reactions [PDF]

open access: yes
Three investigations conducted aboard Skylab IV and Apollo-Soyuz involved phenomena that are of interest to the biochemistry community. The formaldehyde clock reaction and the equilibrium shift reaction experiments conducted aboard Apollo Soyuz ...
Facemire, B., Grodzka, P.
core   +1 more source

Proton FLASH Exposure Preserves Gut Commensal Microbiomes and Spares Intestinal Stem Cells

open access: yesAdvanced Science, EarlyView.
This study highlights the role of Proton FLASH abdominal irradiation in sparing of intestinal stem cells and preservation of key gut microbial population resulting minimization of radiation toxicity in intestinal epithelium in mice. Our findings support the potential of Proton FLASH to improve the therapeutic ratio for abdominal radiation exposure ...
Rishi Man Chugh   +11 more
wiley   +1 more source

Thermally Activated Delayed Fluorescence Carbazole Dendrimers

open access: yesThermally Activated Delayed Fluorescence Carbazole Dendrimers
identifier:oai:t2r2.star.titech.ac.jp ...
openaire  

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