Results 51 to 60 of about 9,144 (206)

Time‐Multiplexed Organic Electrochemical Transistor for Saliva‐Based Rapid Detection of Viral Proteins

open access: yesAdvanced Science, EarlyView.
A time‐multiplexed nanobody‐functionalized organic electrochemical transistor enables rapid and sensitive detection of three respiratory viral proteins from saliva. Sequentially addressed multi‐gate electrodes on a shared channel achieve around 1 fm detection within 15 min without sample preprocessing. Clinical validation demonstrates high specificity,
Tianrui Chang   +13 more
wiley   +1 more source

Effects of wall slip and nanoparticles' thermophoresis on the convective heat transfer enhancement of nanofluid in a microchannel

open access: yesJournal of Thermal Science and Technology, 2016
Heat transfer enhancement with nanofluid appears to be an attractive work in recent years. In present work, a numerical formulation based on the Buongiorno model for convective heat transfer using Al2O3-water nanofluid accounted for the effects of ...
Ruijin WANG, Jiayou DU, Zefei ZHU
doaj   +1 more source

A Hidden Anomaly in the Binary Mixture Natural Convection Subject to Flux Boundary Conditions

open access: yesPhysics, 2021
The problem of natural convection in a binary mixture subject to realistic boundary conditions of imposed zero mass flux on the solid walls shows solutions that might lead to unrealistic negative values of the mass fraction (or solute concentration ...
Peter Vadasz
doaj   +1 more source

Molecular Editing Reveals a Bilobalide Chemotype that Attenuates Prolyl Endopeptidase (PREP)‐Linked Neuroinflammation

open access: yesAdvanced Science, EarlyView.
Molecular editing of bilobalide uncovers BB56, a PREP‐engaging chemotype with enhanced anti‐inflammatory activity in microglia. Integrated CETSA‐MS, SAR, and pathway analyses link BB56 to attenuation of p38 MAPK/NF‐κB and NLRP3‐associated inflammatory signaling, highlighting bilobalide editing as a strategy for developing neuroinflammation‐modulating ...
Chanin Sillapachaiyaporn   +20 more
wiley   +1 more source

MODELING OF ASPHALTENE DEPOSITION IN PIPELINES [PDF]

open access: yesJournal of Petroleum Science and Technology, 2013
This paper is concerned with asphaltene deposition in fluid flowing through pipelines. Brownian diffusion and drag, gravitational, thermophoresis, buoyancy, and shear removal are considered as possible mechanisms in the asphaltene deposition process. The
Behruz Mirzayi   +2 more
doaj   +1 more source

NAT10‐Mediated ac4C Modification of circANKRD12 Reprograms the Tumor Microenvironment

open access: yesAdvanced Science, EarlyView.
NAT10‐dependent acetylation of circANKRD12 drives translation of the circANKRD12_354aa protein, which binds HDAC2 to stabilize c‐Myc via deubiquitination, promoting multiple myeloma (MM) cell proliferation. Concurrently, the circANKRD12‐HDAC2 axis suppresses H3ac‐mediated transcription of IFN‐γ, TNF‐α, and GZMB in NK cells, leading to NK cell ...
Jiale Zhang   +8 more
wiley   +1 more source

Conductometric Soot Sensors: Internally Caused Thermophoresis as an Important Undesired Side Effect

open access: yesSensors, 2018
Particulate matter sensors are of interest for application in the exhaust of any combustion processes, especially for automotive aftertreatment systems. Conductometric soot sensors have been serialized recently.
Gunter Hagen   +5 more
doaj   +1 more source

Power-Law Nanofluid Flow over a Stretchable Surface Due to Gyrotactic Microorganisms

open access: yesMathematics, 2022
This study aims to learn more about how the flow of a power-law nanofluid’s mixed bio-convective stagnation point flow approaching a stretchable surface behaves with the presence of a passively controlled boundary condition.
Hossam A. Nabwey   +4 more
doaj   +1 more source

AI‐Designed Cyclic Peptides Enable Controllable Modulation of the CD28 Immune Checkpoint

open access: yesAdvanced Science, EarlyView.
AI‐designed cyclic peptides enable controllable modulation of the CD28 immune checkpoint through reversible disruption of CD28‐CD80/CD86 interactions. The lead peptide, CIP‐3, suppresses T‐cell activation without intrinsic agonist activity, demonstrates dose‐dependent efficacy in a murine colitis model, and attenuates inflammatory cytokine production ...
Katarzyna Kuncewicz   +4 more
wiley   +1 more source

Homotopy Semi-Numerical Modeling of Non-Newtonian Nanofluid Transport External to Multiple Geometries Using a Revised Buongiorno Model

open access: yesInventions, 2019
A semi-analytical solution for the convection of a power-law nanofluid external to three different geometries (i.e., cone, wedge and plate), subject to convective boundary condition is presented.
Atul Kumar Ray   +4 more
doaj   +1 more source

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