Results 61 to 70 of about 10,770 (259)

Controlled Movement of Soft Actuators using Multi‐Responsive Microgel Arrays and Microcirculatory Systems

open access: yesAdvanced Functional Materials, EarlyView.
Microscale hydrogels (microgels) feature improved mass transport characteristics supportive of fast actuation and chemical tunability amenable to programmed stimuli response. A unique soft actuator architecture is realized by encapsulating microgels in soft microcirculatory systems which enable the convenient delivery of liquid stimuli for powering and
Nengjian Huang   +2 more
wiley   +1 more source

Tuning Pluronic Hydrogel Networks: Effects of Vancomycin Loading on Gelation, Rheological Properties, and Micellar Structures

open access: yesGels
Thermoresponsive Pluronic hydrogels offer a promising platform for localised antibiotic delivery. However, how drug loading affects the structural integrity and gelation of these systems remains underexplored.
Michael J. Gaffney   +3 more
doaj   +1 more source

Preparation and Investigation of Poly (N-isopropylacrylamide-acrylamide) Membranes in Temperature Responsive Drug Delivery [PDF]

open access: yes, 2009
Objective(s)Physiological changes in the body may be utilized as potential triggers for controlled drug delivery. Based on these mechanisms, stimulus–responsive drug delivery has been developed.Materials and MethodsIn this study, a kind of poly (N ...
Afshin Jalali   +4 more
core  

Core-sheath nanofibers as drug delivery system for thermoresponsive controlled release [PDF]

open access: yes, 2017
In this work, a smart drug delivery system of core–sheath nanofiber is reported. The core-sheath nanofibers were prepared with thermoresponsive poly-(N-isopropylacrylamide) (PNIPAAm) (as core) and hydrophobic ethylcellulose (EC) (as sheath) by coaxial ...
Chen   +42 more
core   +1 more source

Adaptive 4D‐Printed Vascular Stents With Low‐Temperature‐Activated and Intelligent Deployment

open access: yesAdvanced Functional Materials, EarlyView.
Microarchitected coronary artery stents were fabricated using a polycaprolactone (PCL)‐based shape memory polymer (SMP) composite via projection micro‐stereolithography (PµSL) 4D printing. By incorporating diethyl phthalate (DEP) as a plasticizer, the thermal transition temperature (Ttran) was modulated to about 37°C, enabling rapid and autonomous ...
Yannan Li   +12 more
wiley   +1 more source

A mucosa-mimetic material for the mucoadhesion testing of thermogelling semi-solids [PDF]

open access: yes, 2017
Mucosa-mimetic materials are synthetic substrates which aim to replace animal tissue in mucoadhesion experiments. One potential mucosa-mimetic material is a hydrogel comprised of N-acryloyl-d-glucosamine and 2-hydroxyethylmethacrylate, which has been ...
Bruschi, Marcos L.   +3 more
core   +3 more sources

Thermoresponsive and Injectable Hydrogel for Tissue Agnostic Regeneration

open access: yesAdvanced Healthcare Materials, 2022
AbstractInjectable hydrogels can support the body's innate healing capability by providing a temporary matrix for host cell ingrowth and neovascularization. The clinical adoption of current injectable systems remains low due to their cumbersome preparation requirements, device malfunction, product dislodgment during administration, and uncontrolled ...
Dax Calder   +22 more
openaire   +2 more sources

Bio‐Orthogonally Crosslinked Supramolecular Polymer Bottlebrush Hydrogels for Long‐Term 3D Cell Culture

open access: yesAdvanced Functional Materials, EarlyView.
Fibrous benzenetrispeptide (BTP) hydrogels, fabricated via strain‐promoted azide‐alkyne cycloaddition (SPAAC) crosslinking, form robust, bioinert networks. These hydrogels can support 3D cell culture, where cell viability and colony growth depend on the fiber content.
Ceren C. Pihlamagi   +5 more
wiley   +1 more source

UV‐Induced Photopatterning of the Thermoresponsive Properties of a Poly(ethylene glycol)methylether acrylate‐co‐poly(N‐isopropylacrylamide) Hydrogel

open access: yesSmall Structures
Photopatterning offers a versatile and precise approach for modifying surface properties, making it a valuable technique in material design. Recent research demonstrates that polymer swelling can significantly enhance photodegradation, facilitating ...
Qian‐Pu Cheng   +3 more
doaj   +1 more source

Advanced Hydrogel Systems for Local Anesthetic Delivery: Toward Prolonged and Targeted Pain Relief

open access: yesGels
Local anesthetics (LAs) have been indispensable in clinical pain management, yet their limitations, such as short duration of action and systemic toxicity, necessitate improved delivery strategies.
Jin-Oh Jeong   +4 more
doaj   +1 more source

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