Results 21 to 30 of about 1,287 (150)

The physiological role of TRP channels in sleep and circadian rhythm. [PDF]

open access: yesJ Cell Mol Med
Abstract TRP channels, are non‐specific cationic channels that are involved in multiple physiological processes that include salivation, cellular secretions, memory extinction and consolidation, temperature, pain, store‐operated calcium entry, thermosensation and functionality of the nervous system.
Woodard GE, Rosado JA, Li H.
europepmc   +2 more sources

Hydrogen‐Bonded Cholesteric Liquid Crystals—A Modular Approach Toward Responsive Photonic Materials

open access: yesAdvanced Photonics Research, 2022
A supramolecular approach for photonic materials based on hydrogen‐bonded cholesteric liquid crystals is presented. The modular toolbox of low‐molecular‐weight hydrogen‐bond donors and acceptors provides a simple route toward liquid crystalline materials
Florian Malotke   +5 more
doaj   +1 more source

Cells and circuits for thermosensation in mammals [PDF]

open access: yesNeuroscience Letters, 2019
How is temperature detected and how is the resulting sensory information synthesized to produce appropriate thermosensory responses? Research in the last few years has gone a long way to answering the first part of this question. Excitingly, recent research has uncovered some of the ways sensory inputs are processed spinally, as well as identifying ...
Hans Jürgen, Solinski, Mark A, Hoon
openaire   +2 more sources

The role of TRPA1 channels in thermosensation

open access: yesCell Insight, 2022
Transient receptor potential ankyrin 1 (TRPA1) is a polymodal nonselective cation channel sensitive to different physical and chemical stimuli. TRPA1 is associated with many important physiological functions in different species and thus is involved in different degrees of evolution.
Hao Zhang   +6 more
openaire   +3 more sources

Thermosensing Enlightened

open access: yesTrends in Plant Science, 2017
Understanding the molecular networks driving plant responses to high ambient temperatures is crucial for developing crop cultivars resistant to global warming. Although several factors involved in temperature signalling are known, a thermosensing mechanism had remained elusive.
Delker, Carolin   +2 more
openaire   +4 more sources

Engineering vanilloid-sensitivity into the rat TRPV2 channel

open access: yeseLife, 2016
The TRPV1 channel is a detector of noxious stimuli, including heat, acidosis, vanilloid compounds and lipids. The gating mechanisms of the related TRPV2 channel are poorly understood because selective high affinity ligands are not available, and the ...
Feng Zhang   +8 more
doaj   +1 more source

Structural insights into the mechanism of activation of the TRPV1 channel by a membrane-bound tarantula toxin

open access: yeseLife, 2016
Venom toxins are invaluable tools for exploring the structure and mechanisms of ion channels. Here, we solve the structure of double-knot toxin (DkTx), a tarantula toxin that activates the heat-activated TRPV1 channel. We also provide improved structures
Chanhyung Bae   +10 more
doaj   +1 more source

Injury Threshold of Oral Contact with Hot Foods and Method for Its Sensory Evaluation

open access: yesSafety, 2018
Epidemiological studies indicate an increased risk of esophageal cancer from the consumption of very hot foods and beverages. The contact time and the contact temperature are decisive for the risk of injury.
Dirk W. Lachenmeier, Walter Lachenmeier
doaj   +1 more source

Transmembrane Prolines Mediate Signal Sensing and Decoding in Bacillus subtilis DesK Histidine Kinase

open access: yesmBio, 2019
Environmental awareness is an essential attribute of all organisms. The homeoviscous adaptation system of Bacillus subtilis provides a powerful experimental model for the investigation of stimulus detection and signaling mechanisms at the molecular level.
Pilar Fernández   +6 more
doaj   +1 more source

RNA thermosensors facilitate Streptococcus pneumoniae and Haemophilus influenzae immune evasion.

open access: yesPLoS Pathogens, 2021
Bacterial meningitis is a major cause of death and disability in children worldwide. Two human restricted respiratory pathogens, Streptococcus pneumoniae and Haemophilus influenzae, are the major causative agents of bacterial meningitis, attributing to ...
Hannes Eichner   +6 more
doaj   +1 more source

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