Results 31 to 40 of about 1,909 (193)
The role of TRPA1 channels in thermosensation
Cell Insight, 2022 Transient receptor potential ankyrin 1 (TRPA1) is a polymodal nonselective cation channel sensitive to different physical and chemical stimuli. TRPA1 is associated with many important physiological functions in different species and thus is involved in different degrees of evolution.
Hao Zhang +6 more
openaire +3 more sources
eLife, 2016 Venom toxins are invaluable tools for exploring the structure and mechanisms of ion channels. Here, we solve the structure of double-knot toxin (DkTx), a tarantula toxin that activates the heat-activated TRPV1 channel. We also provide improved structures
Chanhyung Bae +10 more
doaj +1 more source
Daytime temperature is sensed by phytochrome B in Arabidopsis through a transcriptional activator HEMERA. [PDF]
, 2019 Ambient temperature sensing by phytochrome B (PHYB) in Arabidopsis is thought to operate mainly at night. Here we show that PHYB plays an equally critical role in temperature sensing during the daytime.
Chen, Meng +4 more
core +3 more sources
Engineering vanilloid-sensitivity into the rat TRPV2 channel
eLife, 2016 The TRPV1 channel is a detector of noxious stimuli, including heat, acidosis, vanilloid compounds and lipids. The gating mechanisms of the related TRPV2 channel are poorly understood because selective high affinity ligands are not available, and the ...
Feng Zhang +8 more
doaj +1 more source
Foods, 2018 The International Agency for Research on Cancer (IARC) evaluates “very hot (>65 °C) beverages” as probably carcinogenic to humans. However, there is a lack of research regarding what temperatures consumers actually perceive as &ldquo ...
Julia Dirler +2 more
doaj +1 more source
RNA thermosensors facilitate Streptococcus pneumoniae and Haemophilus influenzae immune evasion.
PLoS Pathogens, 2021 Bacterial meningitis is a major cause of death and disability in children worldwide. Two human restricted respiratory pathogens, Streptococcus pneumoniae and Haemophilus influenzae, are the major causative agents of bacterial meningitis, attributing to ...
Hannes Eichner +6 more
doaj +1 more source
Crystals, 2021 Photoluminescent liquid crystals (PLLCs) have attracted significant attention owing to their broad applicability in thermosensing and PL switching.
Shigeyuki Yamada +10 more
doaj +1 more source
Crystal structure of a thermophilic GrpE protein: insight into thermosensing function for the DnaK chaperone system. [PDF]
, 2010 A homodimeric GrpE protein functions as a nucleotide exchange factor of the eubacterium DnaK molecular chaperone system. The co-chaperone GrpE accelerates ADP dissociation from, and promotes ATP binding to, DnaK, which cooperatively facilitates the DnaK ...
Miki, Kunio +2 more
core +1 more source
Isolate Specific Cold Response of Yersinia enterocolitica in Transcriptional, Proteomic, and Membrane Physiological Changes [PDF]
, 2020 Yersinia enterocolitica, a zoonotic foodborne pathogen, is able to withstand low temperatures. This psychrotrophic ability allows it to multiply in food stored in refrigerators. However, little is known about the Y. enterocolitica cold response.
Alter, Thomas +4 more
core +1 more source
Fifty years of development of neuroscientific insights into oro‐facial pain and its control
Journal of Oral Rehabilitation, Volume 50, Issue 9, Page 860-876, September 2023., 2023 Abstract When the Journal of Oral Rehabilitation was established in 1973, there was very limited understanding of the mechanisms underlying neurally based functions, including those unique to the face, mouth and jaws (e.g. dental pain, taste, chewing, swallowing and salivation). Since that time, technological and other advances have led to new insights
Barry J. Sessle
wiley +1 more source