Results 81 to 90 of about 1,909 (193)

Functional assessment of temperature-gated ion-channel activity using a real-time PCR machine

BioTechniques, 2009
The functional activity of a number of ion channels is highly sensitive to large changes in temperature. Foremost among these are the thermosensing TRP channels which include cold- (TRPM8, TRPA1), warmth- (TRPV3, TRPV4), and heat-sensing (TRPV1, TRPV2 ...
Derek S. Reubish, Daniel E. Emerling, Jeff DeFalco, Daniel Steiger, Cheryl L. Victoria, Fabien Vincent   +5 more
doaj   +1 more source

Measurement and Control of Single Nitrogen-Vacancy Center Spins above 600 K

, 2012
We study the spin and orbital dynamics of single nitrogen-vacancy (NV) centers in diamond between room temperature and 700 K. We find that the ability to optically address and coherently control single spins above room temperature is limited by ...
Alkauskas, A., Awschalom, D. D., Buckley, B. B., Christle, D. J., Toyli, D. M., Van de Walle, C. G.   +5 more
core   +2 more sources

The secreted autotransporter toxin (Sat) does not act as a virulence factor in the probiotic Escherichia coli strain Nissle 1917 [PDF]

, 2015
BACKGROUND: Escherichia coli Nissle 1917 (EcN) is a probiotic used in the treatment of intestinal diseases. Although it is considered safe, EcN is closely related to the uropathogenic E.
Aguilera Gil, Maria Laura, Alvarez Villagomez, Carina Shianya, Badía Palacín, Josefa, Baldomà Llavinés, Laura, Cañas Pacheco, María Alexandra, Fábrega Fernández, María José, Giménez Claudio, Rosa, Martín Venegas, Raquel, Toloza Maturana, Lorena   +8 more
core   +1 more source

'Add, stir and reduce': Yersinia spp. as model bacteria for pathogen evolution [PDF]

, 2016
In the study of molecular microbiology and bacterial genetics, pathogenic species of the Yersinia genus have been pillars for research aimed at understanding how bacteria evolve into mammalian pathogens.
McNally, A, Reuter, S, Thomson, NR, Wren, BW   +3 more
core   +4 more sources

Gene Regulatory Changes Associated With Phenological Transitions in an Ecologically Significant Tree Species

Plant-Environment Interactions, Volume 6, Issue 4, August 2025.
Climate change is driving earlier spring leaf‐out across temperate regions, but the genetic mechanisms and environmental interactions underlying this variability are poorly understood. We conducted a controlled growth chamber experiment using excised northern red oak (Quercus rubra) branches, testing the influence of temperature and photoperiod on leaf
Theresa Caso‐McHugh, David L. Des Marais, Miranda Oseguera, Meghan Blumstein   +3 more
wiley   +1 more source

Cerulenin inhibits unsaturated fatty acids synthesis in Bacillus subtilis by modifying the input signal of DesK thermosensor [PDF]

, 2014
Bacillus subtilis responds to a sudden decrease in temperature by transiently inducing the expression of the des gene encoding for a lipid desaturase, D5-Des, which introduces a double bond into the acyl chain of preexisting membrane phospholipids.
Altabe, Silvia Graciela, Cybulski, Larisa Estefania, de Mendoza, Diego, Mansilla, Maria Cecilia, Porrini, Lucía   +4 more
core   +1 more source

Genetics‐Based Targeting Strategies for Precise Neuromodulation

Advanced Science, Volume 12, Issue 28, July 24, 2025.
In this Review, the fundamental principles and implementation protocols of genetics‐based precision neuromodulation are first introduced. Then, wireless and low‐invasive strategies based on nano‐transducing materials are highlighted, along with a dissection and analysis of the strengths and weaknesses of representative studies.
Yuyuan He, Zhidong Wei, Jianda Xu, Fei Jin, Tong Li, Lili Qian, Juan Ma, Weiying Zheng, Negar Javanmardi, Ting Wang, Kangjian Sun, Zhang‐Qi Feng   +11 more
wiley   +1 more source

TRP ion channels in thermosensation, thermoregulation and metabolism [PDF]

Temperature, 2015
In humans, the TRP superfamily of cation channels includes 27 related molecules that respond to a remarkable variety of chemical and physical stimuli. While physiological roles for many TRP channels remain unknown, over the past years several have been shown to function as molecular sensors in organisms ranging from yeast to humans.
Hong Wang, Jan Siemens
openaire   +2 more sources

RETINOBLASTOMA‐RELATED Has Both Canonical and Noncanonical Regulatory Functions During Thermo‐Morphogenic Responses in Arabidopsis Seedlings

Plant, Cell &Environment, Volume 48, Issue 2, Page 1217-1231, February 2025.
ABSTRACT Warm temperatures accelerate plant growth, but the underlying molecular mechanism is not fully understood. Here, we show that increasing the temperature from 22°C to 28°C rapidly activates proliferation in the apical shoot and root meristems of wild‐type Arabidopsis seedlings.
Rasik Shiekh Bin Hamid, Fruzsina Nagy, Nikolett Kaszler, Ildikó Domonkos, Magdolna Gombos, Annamária Marton, Csaba Vizler, Eszter Molnár, Aladár Pettkó‐Szandtner, László Bögre, Attila Fehér, Zoltán Magyar   +11 more
wiley   +1 more source

Heat application in live cell imaging

FEBS Open Bio, Volume 14, Issue 12, Page 1940-1954, December 2024.
Thermal modulation in live‐cell imaging with a high spatiotemporal resolution allows the investigation of biomolecular reactions like protein deactivation and unfolding, and cellular processes like calcium signaling. Local changes in temperature are induced via infrared (IR) irradiation of water (direct), magnetic or radiative excitation of absorber ...
Linda Sistemich, Simon Ebbinghaus
wiley   +1 more source