Results 1 to 10 of about 23,894 (119)

A Comprehensive Review of Thermosensitive Hydrogels: Mechanism, Optimization Strategies, and Applications

Gels
Thermosensitive hydrogels undergo reversible sol-gel phase transitions in response to changes in temperature. Owing to their excellent biocompatibility, mild reaction conditions, and controllable gelation properties, these hydrogels represent a promising
Yumin Heng
exaly   +3 more sources

Hyaluronic Acid-Binding, Anionic, Nanoparticles Inhibit ECM Degradation and Restore Compressive Stiffness in Aggrecan-Depleted Articular Cartilage Explants

Pharmaceutics, 2021
Joint trauma results in the production of inflammatory cytokines that stimulate the secretion of catabolic enzymes, which degrade articular cartilage.
Marcus Deloney, Parssa Garoosi, Vanessa F. C. Dartora, Blaine A. Christiansen, Alyssa Panitch   +4 more
doaj   +1 more source

A Novel Method for the Preparation of Poly (Acrylamide-co-Acrylonitrile) Upper Critical Solution Temperature Thermosensitive Hydrogel by the Partial Dehydration of Acrylamide Grafted Polypropylene Sheets

Gels, 2022
In an attempt to find a potential application of cell culture harvesting, a novel method for the preparation of an upper critical solution temperature (UCST) thermosensitive hydrogel was studied. An electron accelerator was used as the electron beam (EB)
Yi Ling, Liuyuchen Chen, Mingjun Huang, Cheng Zhou, Liming Yang, Hejingying Niu, Li Su, Yuejiao Yang, Rogério P. Pirraco, Rui L. Reis, Jie Chen   +10 more
doaj   +1 more source

Smart Hydrogel Formed by Alginate-g-Poly(N-isopropylacrylamide) and Chitosan through Polyelectrolyte Complexation and Its Controlled Release Properties

Gels, 2022
Smart hydrogels that can respond to external stimuli such as temperature and pH have attracted tremendous interest for biological and biomedical applications.
Min Liu, Jingling Zhu, Xia Song, Yuting Wen, Jun Li   +4 more
doaj   +1 more source

Injectable Thermosensitive Hyaluronic Acid Hydrogels for Chondrocyte Delivery in Cartilage Tissue Engineering

Pharmaceuticals, 2023
In this study, we synthesize a hyaluronic acid-g-poly(N-isopropylacrylamide) (HPN) copolymer by grafting the amine-terminated poly(N-isopropylacrylamide) (PNIPAM-NH2) to hyaluronic acid (HA).
Chih-Hao Chen, Hao-Hsi Kao, Yen-Chen Lee, Jyh-Ping Chen   +3 more
doaj   +1 more source

Thermosensitive Polyester Hydrogel for Application of Immunosuppressive Drug Delivery System in Skin Allograft

Gels, 2021
Tacrolimus (FK506) is a common immunosuppressive drug that is capable of suppressing acute rejection reactions, and is used to treat patients after allotransplantation.
I-En Wu, Madonna Rica Anggelia, Sih-Yu Lin, Chiao-Yun Chen, I-Ming Chu, Cheng-Hung Lin   +5 more
doaj   +1 more source

Design of DOX-GNRs-PNIPAM@PEG-PLA Micelle With Temperature and Light Dual-Function for Potent Melanoma Therapy

Frontiers in Chemistry, 2021
Objective: The aim of this study was to construct light and temperature dual-sensitive micellar carriers loaded with doxorubicin (DOX) and gold nanorods (DOX-GNRs-PNIPAM@PEG-PLA, DAPP) for melanoma therapy.Methods: The DAPP self-assembled using fine ...
Na Wang, Jing Shi, Cong Wu, Weiwei Chu, Wanru Tao, Wei Li, Xiaohai Yuan   +6 more
doaj   +1 more source

The Properties of Thermosensitive Zwitterionic Sulfobetaine NIPAM-co-DMAAPS Polymer and the Hydrogels: The Effects of Monomer Concentration on the Transition Temperature and Its Correlation with the Adsorption Behavior

Indonesian Journal of Chemistry, 2020
The properties of N-isopropylacrylamide copolymerized with N,N-dimethyl(acrylamidopropyl)ammonium propane sulfonate [poly(NIPAM-co-DMAAPS)] prepared with various monomer ratios such as transition temperature, molecular structure, viscosity were ...
Eva Oktavia Ningrum, Agus Purwanto, Galuh Chynintya Rosita, Asep Bagus   +3 more
doaj   +1 more source

Injectable and Temperature-Sensitive Titanium Carbide-Loaded Hydrogel System for Photothermal Therapy of Breast Cancer

Frontiers in Bioengineering and Biotechnology, 2021
Recently, organic–inorganic hybrid materials have gained much attention as effective photothermal agents for cancer treatment. In this study, Pluronic F127 hydrogel-coated titanium carbide (Ti3C2) nanoparticles were utilized as an injectable photothermal
Jun Yao, Chuanda Zhu, Tianjiao Peng, Qiang Ma, Shegan Gao   +4 more
doaj   +1 more source

Behavior of PNIPAM Microgels in Different Organic Solvents

Molecules, 2022
In this research, we studied, in detail, the behavior of common PNIPAM microgels, obtained through surfactant-free precipitation polymerization, in a number of organic solvents.
Galina A. Komarova, Elena Yu. Kozhunova, Igor I. Potemkin   +2 more
doaj   +1 more source