Results 101 to 110 of about 4,870 (321)

Learning to Shift Thermostatically Controlled Loads [PDF]

Proceedings of the Annual Hawaii International Conference on System Sciences, 2017
Antoine Lesage-Landry, Joshua A. Taylor
openaire   +1 more source

Hepatocyte BDNF Acts as a Novel Immune Checkpoint to Restrain TLR4‐Mediated Acute Hepatitis

Advanced Science, EarlyView.
This study identifies hepatocyte‐derived BDNF as an endogenous TLR4 antagonist that alleviates acute hepatitis. BDNF is downregulated in hepatocytes via REST‐mediated transcriptional repression during ALI/ALF. Mechanistically, BDNF binds to TLR4 on macrophages to suppress inflammation.
Weiwei Zhu, Yaqian Cui, Yongqiang Zhou, Yihui Zheng, Lijiang Huang, Leiming Jin, Qianhui Zhang, Pan Chen, Mengsha Lin, Jiaxi Ye, Yongqiang Xiong, Joo Young Huh, Xiang Hu, Xiaokun Li, Wu Luo, Guang Liang   +15 more
wiley   +1 more source

Phosphatidic Acid‐TRIM59‐Olig2 Signaling Couples Metabolic Dysfunction to Myelination Failure in PWMI

Advanced Science, EarlyView.
PA accumulates after hypoxic‐ischemic injury and stabilizes the E3 ligase TRIM59 in OPCs. Stabilized TRIM59 enhances ubiquitination and degradation of Olig2, blocking differentiation and causing hypomyelination in PWMI. Modulating PA synthesis restores Olig2 levels, improves myelination, and ameliorates behavioral deficits, defining a metabolically ...
Xinyu Li, Yanan Liu, Meng Zhang, Yiwei Liu, Meiting Liu, Kaishen Zhu, Zhian Liu, Chao Ren, Ruiqin Yao   +8 more
wiley   +1 more source

Ultra-high temperature stability Joule-Thomson cooler with capability to accomodate pressure variations [PDF]

, 1992
A Joule-Thomson cryogenic refrigeration system capable of achieving high temperature stabilities in the presence of varying temperature, atmospheric pressure, and heat load is provided.
Bard, Steven, Trimble, Curtis A., Wu, Jiunn-Jeng   +2 more
core   +1 more source

Rapid Steam‐Assisted Temperature Swing Adsorption for Direct Air Capture Using a Rotary Adsorber

Advanced Science, EarlyView.
This study presents a direct air capture (DAC) device based on a steam‐regeneration rotary adsorber for high‐purity CO2. Testing of the prototype demonstrates its capability for continuous and stable carbon capture with the potential to achieve ton‐scale.
Junye Wu, Yunhao Chen, Kuihua Wang, Yingjie Huo, Yanlin Chen, Quanwen Pan, Tianshu Ge   +6 more
wiley   +1 more source

Highly Sensitive and Temperature‐Insensitive Stretchable Strain Sensor with Microcrack‐Engineered Architecture

Advanced Science, EarlyView.
This study proposes a stretchable strain sensor that demonstrates a high gauge factor of 2.3 × 104 and excellent linearity (R2 = 0.98), while maintaining temperature insensitivity under applied strain. This performance is achieved through a microcrack architecture formed by stacking a brittle, low‐resistance material with a stretchable, high‐resistance
Yu Kato, Kento Yamagishi, Kenjiro Fukuda, Takao Someya, Tomoyuki Yokota   +4 more
wiley   +1 more source

Direct load control of thermostatically controlled loads based on sparse observations using deep reinforcement learning

CSEE Journal of Power and Energy Systems, 2019
This paper considers a demand response agent that must find a near-optimal sequence of decisions based on sparse observations of its environment.
Frederik Ruelens, Bert J. Claessens, Peter Vrancx, Fred Spiessens, Geert Deconinck   +4 more
doaj   +1 more source

An ATP‐Mediated Antibiotic β‐Peptide Nanofiber That Kills Multidrug‐Resistant Bacteria via a Multistage Mechanism

Advanced Science, EarlyView.
The 3K‐AP system forms infinite supramolecular fibrils that undergo controlled degradation into shorter fragments upon enzymatic hydrolysis. Multitechnique imaging reveals a stepwise bacteriolytic mechanism involving bacterial entrapment, disassembly into lethal constructs, and associated extracellular vesicle release, highlighting the dynamic ...
Sohini Chakraborty, Kamal el Battioui, Dániel Molnár, Bálint Jezsó, Lejla Daruka, Tasvilla Sonallya, Tünde Juhász, Rita Hirmondó, Imola Cs. Szigyártó, Loránd Románszki, Natália Tőkési, Daniel Pinkas, Eszter Házy, Olivér Pavela, Andrea Bodor, Zoltán Varga, István Mándity, Mihály Kovács, Csaba Pál, Kata Horváti, Judit Tóth, Tamás Beke‐Somfai   +21 more
wiley   +1 more source

Optimal provision of distributed reserves under dynamic energy service preferences [PDF]

, 2018
We propose and solve a stochastic dynamic programming (DP) problem addressing the optimal provision of regulation service reserves (RSR) by controlling dynamic demand preferences in smart buildings.
Baillieul, John, Caramanis, M. C., Zhang, B.   +2 more
core  

Deformation‐Induced Formation of Stray Grains in Additive Manufacturing of Single Crystals

Advanced Science, EarlyView.
Stray grain formation severely limits the additive manufacturing of single‐crystal alloys. By integrating in situ synchrotron techniques, ex situ characterization, and multi‐scale multi‐physics modeling, the authors reveal that stray grains originate from dislocations at the solid‐liquid interface, rather than thermal supercooling in conventional ...
Dongsheng Zhang, Zixu Guo, Yuxiao Li, Lu Wang, Yu Wu, Darui Sun, Wentao Yan, Yuanyuan Guo, Han Wang, Wei Liu, Ye Tao, Bingbing Zhang   +11 more
wiley   +1 more source