Results 201 to 210 of about 633,217 (290)

Evolution of N‐terminal mechanical lability as a determinant for Type III secretion

Protein Science, Volume 35, Issue 8, August 2026.
Abstract Many Gram‐negative pathogens critically depend on the Type III secretion system (T3SS) to inject effector proteins into host cells for colonization. Because the channel of the T3SS is narrow (~2 nm), effectors must be unfolded for secretion.
Katherine E. DaPron, Alexandre M. Plastow, Morgan R. Fink, Brandon Dzuba, Marc‐Andre LeBlanc, Thomas T. Perkins, Emad Tajkhorshid, Marcelo C. Sousa   +7 more
wiley   +1 more source

Development of Low-Dose Disulfiram Rectal Suppository Intended for Application in Post-Treatment Lyme Disease Syndrome. [PDF]

Pharmaceutics
Benkő BM, Szabó BI, Kádár S, Szabó E, Tóth G, Szente L, Tonka-Nagy P, Zelkó R, Sebe I.   +8 more
europepmc   +1 more source

Edge‐Grafted Polyarginine Functionalization of Graphene Nanocarriers Maintains Noncovalent Aromatic Drug Loading

Journal of Peptide Science, Volume 32, Issue 8, August 2026.
Edge‐selective covalent grafting of poly‐arginine‐11 onto B60 graphene nanoparticles preserves the aromatic basal plane for π‐π immobilization of compound 8, highlighting this promising NEK6 inhibitor as the key therapeutic cargo in a peptide‐graphene nanoplatform for potential delivery.
Beatrice Scagnoli, Alessandro Semeraro, Kaiyue Hu, Alberto Ongaro, Agnese Pavan, Luigi Brambilla, Chiara Castiglioni, Maria Cristina De Rosa, Giuseppe Pappalardo, Giuseppina Sabatino, Michele Maggini   +10 more
wiley   +1 more source

Smart and Biodegradable Polymers in Tissue Engineering and Interventional Devices: A Brief Review. [PDF]

Polymers (Basel)
Dallaev R.
europepmc   +1 more source

Activating Paper Applying Gelatin, Starch and Chitosan Coatings Loaded With O/W Emulsions Encapsulating Rutin, Carvacrol and α‐Tocopherol

Packaging Technology and Science, Volume 39, Issue 8, Page 1061-1082, August 2026.
Emulsion type governed the microstructure and functionality of papers coated with biopolymers matrix loaded with hydrophobic bioactives encapsulated into O/W emulsions. Emulsified systems improved UV–Vis barrier and antioxidant activity, whereas gelatin coatings with conventional or Pickering emulsions provided the greatest mechanical reinforcement ...
Kamila de L. Santos, Ana Mônica Quinta Barbosa Bittante, Rodrigo Vinícius Lourenço, Júlio Cesar de Carvalho Balieiro, Paulo José do Amaral Sobral   +4 more
wiley   +1 more source

Vagus nerve stimulation alleviates S. aureus-induced mastitis by regulating gut microbiota S24-7-PPARγ and NF-ΚB/NLRP3 signaling in mice. [PDF]

J Neuroinflammation
He Y, Zhang Y, Zhao L, Zhou Z, Su N, Zhang C, Wang K, Jin L, Yang B, Hu X, Fu Y.   +10 more
europepmc   +1 more source

Citizens' Preferences for Narrow and Broad Security Threats: Evidence From a New NATO Member State

Scandinavian Political Studies, Volume 49, Issue 3, August 2026.
ABSTRACT This study explores citizens' evaluations of competing security threats and prioritizes policy responses using data from Finland. Despite escalating geopolitical tensions and proximity to Russia, Finnish public opinion favors broader human security concerns, such as climate change and organized crime, over traditional military threats. Using a
Anton Brännlund, Albert Weckman, Hanna Wass, Janne Tukiainen, Vesa‐Heikki Soini, Miroslav Nemčok, Isak Vento   +6 more
wiley   +1 more source

Evaluating the protective effects of mouthguards with neutralizing agents against chlorinated water-induced enamel erosion. [PDF]

Front Oral Health
Kitsahawong K, Pitiphat W, Thongpaiboon P, Thongpaiboon S, Saengsuwannarot S.   +4 more
europepmc   +1 more source

Levetiracetam inhibits the Na+ HCO3− transporter Ncbe/NBCn2 (Slc4a10) in the choroid plexus of mice

Acta Physiologica, Volume 242, Issue 8, August 2026.
ABSTRACT Aim The Na+‐dependent Cl−/HCO3− exchanger Ncbe/NBCn2 (Slc4a10) constitutes a major basolateral HCO3− uptake pathway in the choroid plexus and contributes to cerebrospinal fluid secretion and pH regulation. This study examined whether levetiracetam inhibits Ncbe/NBCn2‐mediated transport and alters cerebrospinal fluid acid–base balance ...
Laura Øllegaard Johnsen, Lasse Messell Desdorf, Nicoline Stærke Jensen, Jeppe Praetorius, Helle Hasager Damkier   +4 more
wiley   +1 more source

5‐HT2A receptor agonism by tert‐leucinamide and valinamide synthetic cannabinoids: In vitro and in vivo evidence

British Journal of Pharmacology, Volume 183, Issue 16, Page 4715-4734, August 2026.
Abstract Background and Purpose New synthetic cannabinoid receptor agonists (SCRAs) are associated with severe adverse effects, including unexpected psychiatric symptoms. These compounds are mainly active through their potent agonism on the cannabinoid receptors CB1 and CB2.
Giorgia Corli, Deborah Rudin, Dino Luethi, Matthias E. Liechti, Sabrine Bilel, Matteo Marti, Henrik Green, Manuela Carla Monti, Caitlyn Norman   +8 more
wiley   +1 more source