Results 251 to 260 of about 4,870 (321)
Residues with backbone N‐amination have been introduced into a region of parallel β‐sheet secondary structure. Contrary to predictions, the N‐amination of Trp9 or Phe33 did not give an increase in the thermal stability of DS119. MD simulations suggest this is due to the highly fluctuating nature of the β‐sheet region. ABSTRACT The miniprotein DS119 has
Yushi Qiao +4 more
wiley +1 more source
Unveiling how mitotic spindle orientation in 3D human colon organoids affects matrix displacements through a 4D study using DVC. [PDF]
Magne L +9 more
europepmc +1 more source
ABSTRACT Background Proteolytic processing is a fundamental post‐translational modification. Liquid chromatography–tandem mass spectrometry (LC–MS/MS) workflows are powerful for degradomic analyses but inherently sacrifice spatial information, a critical aspect for investigating biological systems such as aberrant extracellular matrix remodeling and ...
Mujia Jenny Li +8 more
wiley +1 more source
A dam‐inspired textile patch for controllable and quantitative sweat transport (as in dams transporting ships) and sweat loss monitoring. Unlike the conventional Janus‐structured textile of directional water transport model, this textile patch features a multi‐laminated all‐porous fabric structure with an unprecedented layer‐by‐layer isovolumetric ...
Mengyuan Liu +14 more
wiley +1 more source
AI‐assisted design of a VEGFR2 agonistic peptide that promotes angiogenesis and wound repair
Abstract Vascular endothelial growth factor (VEGF) serves as a principal regulator of neovascularization and is essential for vascular regeneration. In this study, we identified and evaluated VEGF Mimetic Peptide3 (VMP3), a novel synthetic peptide developed as a potential VEGFR‐2/VEGF‐A modulator.
Farzana Yasmeen +7 more
wiley +1 more source
Association Between Derivatives of Reactive Oxygen Metabolites and Hemodynamics in Children with Left-to-Right Shunt Congenital Heart Disease. [PDF]
Ishikawa T, Masui D, Uchiyama H.
europepmc +1 more source
ABSTRACT Background In vascular smooth muscle, rises in intracellular calcium [Ca2+]i drive contraction downstream of α1‐adrenoceptor activation via IP3. Endothelium‐derived 6‐nitrodopamine (6‐ND) augments cardiac catecholamine actions; however, its effect on [Ca2+]i is unknown.
José Britto‐Júnior +7 more
wiley +1 more source

