Results 61 to 70 of about 4,291,467 (251)

Spectral Curves of Operators with Elliptic Coefficients

open access: yesSymmetry, Integrability and Geometry: Methods and Applications, 2007
A computer-algebra aided method is carried out, for determining geometric objects associated to differential operators that satisfy the elliptic ansatz.
J. Chris Eilbeck   +2 more
doaj  

Unraveling 4‐Phenylbutyrate's Therapeutic Role in SLC6A1 Disorders: Pharmacochaperoning Over HDAC Inhibition

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Variants in SLC6A1, encoding the GABA transporter 1 (GAT‐1), cause epilepsy, autism spectrum disorder, and developmental delay via loss of GABA uptake, impaired trafficking, and ER retention. We previously found that 4‐Phenylbutyrate (PBA), an FDA‐approved drug, restores GABA uptake and reduces seizures in SLC6A1‐related disorders ...
Melissa B. DeLeeuw   +5 more
wiley   +1 more source

Cosine Integrals for the Clausen Function and Its Fourier Series Expansion

open access: yesInternational Journal of Analysis and Applications, 2017
In a recent work, on taking into account certain finite sums of trigonometric functions I have derived exact closed-form results for some non-trivial integrals, including $\int_0^\pi{\sin(k\,\theta) \, \mathrm{Cl}_2(\theta) \, d \theta}$, where $k$ is a ...
F. M. S. Lima
doaj   +2 more sources

h channel-dependent deficit of theta oscillation resonance and phase shift in temporal lobe epilepsy

open access: yesNeurobiology of Disease, 2009
Ih tunes hippocampal CA1 pyramidal cell dendrites to optimally respond to theta inputs (4–12 Hz), and provides a negative time delay to theta inputs. Decreased Ih activity, as seen in experimental temporal lobe epilepsy (TLE), could significantly alter ...
Béatrice Marcelin   +5 more
doaj   +1 more source

T1 Over Squared Proton Density Ratio to Characterize Multiple Sclerosis Lesions

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Differentiating remyelinated from demyelinated lesions in MS remains challenging without histological confirmation. This study introduces the T1‐to‐PD2 ratio (TPR) imaging approach and evaluates its ability to characterize MS lesions alongside other quantitative MRI (qMRI) metrics. Methods Thirty individuals with MS (mean age: 47.5 ± 
Sarah J. Wright   +10 more
wiley   +1 more source

Zebrafish Polymerase Theta and human Polymerase Theta: Orthologues with homologous function.

open access: yesPLoS ONE
DNA Polymerase Theta (Pol θ) is a conserved an A-family polymerase that plays an essential role in repairing double strand breaks, through micro-homology end joining, and bypassing DNA lesions, through translesion synthesis, to protect genome integrity ...
Corey Thomas   +10 more
doaj   +1 more source

Structure of the Helicase Domain of DNA Polymerase Theta Reveals a Possible Role in the Microhomology-Mediated End-Joining Pathway [PDF]

open access: yes, 2015
DNA polymerase theta (Polθ) has been identified as a crucial alternative non-homologous end-joining factor in mammalian cells. Polθ is upregulated in a range of cancer cell types defective in homologous recombination, and knockdown has been shown to ...
Aitkenhead, H   +8 more
core   +1 more source

Temporal Interference Stimulation of Centromedian‐Parafascicular Complex in Disorders of Consciousness: A Pilot Study

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Treatment of disorders of consciousness (DoC) remains a major clinical challenge, and noninvasive, targeted modulation of deep brain structures has emerged as a promising therapeutic strategy. We aimed to evaluate the feasibility/safety and preliminary effects of thalamic temporal interference stimulation (TIS) targeting centromedian‐
Gengyao Hu   +7 more
wiley   +1 more source

A Family of Theta-Function Identities Based upon Combinatorial Partition Identities Related to Jacobi’s Triple-Product Identity

open access: yesMathematics, 2020
The authors establish a set of six new theta-function identities involving multivariable R-functions which are based upon a number of q-product identities and Jacobi’s celebrated triple-product identity.
Hari Mohan Srivastava   +3 more
doaj   +1 more source

Binary Representations and Theta Function

open access: yesIntegers, 2018
See the abstract in the attached pdf.
George E. Andrews, David Newman
openaire   +3 more sources

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