Results 181 to 190 of about 269,647 (277)

Characterisation of sleep apneas and respiratory circuitry in mice lacking CDKL5

open access: yesJournal of Sleep Research, Volume 34, Issue 2, April 2025.
Summary CDKL5 deficiency disorder is a rare genetic disease caused by mutations in the CDKL5 gene. Central apneas during wakefulness have been reported in patients with CDKL5 deficiency disorder. Studies on CDKL5‐knockout mice, a CDKL5 deficiency disorder model, reported sleep apneas, but it is still unclear whether these events are central (central ...
Gabriele Matteoli   +12 more
wiley   +1 more source

Novel murine closed‐loop auditory stimulation paradigm elicits macrostructural sleep benefits in neurodegeneration

open access: yesJournal of Sleep Research, Volume 34, Issue 2, April 2025.
Summary Boosting slow‐wave activity (SWA) by modulating slow waves through closed‐loop auditory stimulation (CLAS) might provide a powerful non‐pharmacological tool to investigate the link between sleep and neurodegeneration. Here, we established mouse CLAS (mCLAS)‐mediated SWA enhancement and explored its effects on sleep deficits in neurodegeneration,
Inês Dias   +5 more
wiley   +1 more source

Sodium Oxybate Alters Sleep Architecture and Reduces Emotional Selectivity in Memory‐Related Responses

open access: yesJournal of Sleep Research, EarlyView.
ABSTRACT Sleep supports memory consolidation. Non‐rapid eye movement (NREM) and rapid eye movement (REM) sleep have been proposed to support, respectively, declarative memory consolidation and the integration of the memory affective dimension. Here, we used sodium oxybate (SXB) to modify the NREM/REM proportion during one sleep night and assessed ...
Laure Colin   +7 more
wiley   +1 more source

How Mental Concepts Shape Sleep: Introducing the Mental Concept Reactivation Hypothesis of Sleep

open access: yesJournal of Sleep Research, EarlyView.
ABSTRACT Sleep problems affect a substantial proportion of individuals, and negative thoughts, rumination, and worry are considered key factors underlying persistence and severity. While extensive research has examined how these states disrupt sleep before falling asleep, much less is known about how mental concepts, including thoughts, expectations ...
Anna Zoé Wick, Björn Rasch
wiley   +1 more source

A Double‐Blind Randomised Controlled Crossover Trial of the Effect of Blue‐Enriched Ambient Light on Sleep in Older Adults With Sleep Disturbance: The CleverLights Study

open access: yesJournal of Sleep Research, EarlyView.
ABSTRACT Light interventions have been investigated for treating sleep disturbances in older adults; however, findings are mixed. This proof‐of‐concept trial investigated the effect of blue‐enriched ambient light on electroencephalographic (EEG) sleep in older adults with self‐reported poor sleep.
Teha B. Pun   +14 more
wiley   +1 more source

The effects of spectrum, irradiance, and duration of exposure on light‐induced melatonin suppression in healthy adults

open access: yesPhotochemistry and Photobiology, EarlyView.
The left panel reports the measured time course data of melatonin concentration in the blood plasma of 17 BL‐Rs and 15 BL‐NRs at baseline, during a two‐hour stay in the dark, during a one‐hour light exposure to blue light, and again in the dark. The right panel shows the magnitude of melatonin concentration after 60 min of exposure to warm white, cool ...
Helmut Piazena   +4 more
wiley   +1 more source

Grocery Retail Location Patterns in Brno: Clustering, Inequality and Street Network Centrality

open access: yesTijdschrift voor Economische en Sociale Geografie, EarlyView.
Abstract This study aims to evaluate the spatial distribution and clustering patterns of grocery retail chains in Brno, Czech Republic, focusing on national and multinational stores. By employing Geographic Information Systems and advanced spatial analysis techniques, including the nearest neighbour method, standard deviational ellipse, Kernel density ...
Josef Kunc   +5 more
wiley   +1 more source

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