Results 221 to 230 of about 451,694 (312)
Resting‐state EEG revealed that older adults with reduced motor cortex excitability display functional connectivity deficits in cognitive and sensorimotor networks and poorer cognitive performance. These findings suggest that motor excitability indexes early neurophysiological vulnerability and highlight EEG as a sensitive tool for detecting subtle ...
Lorenzo Nucci +9 more
wiley +1 more source
Nocturnal at Noon? Addressing False Positives in Activity Pattern Data
We present a hierarchical Bayesian framework that corrects activity pattern estimates from datasets containing false‐positive detections. We show that our method recovers true activity patterns with high fidelity across multiple activity shapes, false‐positive rates and verification efforts.
Mohamed Khalil Meliane +4 more
wiley +1 more source
Abstract Objective We aimed to study the concordance of seizure semiology in direct electrical stimulation‐induced seizures (SIS) compared to spontaneous seizures during stereoelectroencephalography (SEEG) and to report on patient‐level variables associated with habitual and atypical SIS.
Marai Mahizhnan +5 more
wiley +1 more source
Abstract Objective Characterize electroencephalogram (EEG) dynamics during propofol withdrawal in patients with generalized convulsive status epilepticus (GCSE) and explore their association with functional outcomes. Methods We conducted a retrospective cohort study of adult patients with GCSE who received continuous EEG monitoring and propofol ...
Mathieu Dhoisne +5 more
wiley +1 more source
Unraveling Chronic Pain: From Mechanisms and Risks to Diagnosis and Treatment
Chronic pain arises through distinct molecular pathways categorized into nociceptive, neuropathic, and nociplastic types. Nociceptive pain begins with TRP channel activation in peripheral nociceptors, signaling via Aδ‐ and C‐fibers through the spinal dorsal horn and spinothalamic tracts to the brain, regulated by descending inhibition and involving ...
Xiaofeng Dai +3 more
wiley +1 more source
Free‐Breathing, 3D Cardiac Magnetic Resonance Elastography for Myocardial Stiffness Mapping
ABSTRACT Purpose Magnetic resonance elastography (MRE) of the heart has predominantly utilized breath‐held acquisitions with limited anatomic coverage. This work investigates the feasibility of 3D, free‐breathing cardiac MRE. Methods A 3D hybrid radial and EPI acquisition is utilized and combined with retrospective binning of k‐space via physiologic ...
Nolan K. Meyer +14 more
wiley +1 more source
Exploring small‐world brain connectivity in aging and its relationship with cognitive reserve
Abstract INTRODUCTION The aging brain's vulnerability to decline emphasizes the importance of strategies preserving cognitive function and independence. As age‐related brain changes do not always match clinical symptoms, reserve, encompassing brain reserve (BR) and cognitive reserve (CR), has emerged as a key mechanism supporting resilience and ...
Chiara Pappalettera +13 more
wiley +1 more source
This graphical abstract shows that gut luminal exosomes (LFEs) change with aging, with old mice producing LFEs that disrupt gut barrier integrity, alter microbiome composition, and promote insulin resistance. In contrast, LFEs from young mice improve gut barrier function and metabolic health, and transferring these LFEs can partially reverse age ...
Abdelnaby Khalyfa +3 more
wiley +1 more source
This study presents a pipeline for analysing source‐level brain connectivity in MEG data, focusing on audio‐visual integration in native Chinese speakers and a control group. Results indicate a crucial role of Delta band connectivity, with native speakers showing distinct pathways between prefrontal and occipital, and also interhemispheric brain areas,
Harald Bornfleth +6 more
wiley +1 more source
During an auditory deviance detection task, naïve mice and mice injected with sub‐anesthetic ketamine show marked differences in spiking activity and mesoscale connectivity. Control mice exhibit a biphasic spiking response to deviant sounds, whereas the late spiking component is abolished by ketamine.
Maria Isabel Carreño‐Muñoz +4 more
wiley +1 more source

