Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Variants in SLC6A1, encoding the GABA transporter 1 (GAT‐1), cause epilepsy, autism spectrum disorder, and developmental delay via loss of GABA uptake, impaired trafficking, and ER retention. We previously found that 4‐Phenylbutyrate (PBA), an FDA‐approved drug, restores GABA uptake and reduces seizures in SLC6A1‐related disorders ...
Melissa B. DeLeeuw +5 more
wiley +1 more source
Independent theta phase coding accounts for CA1 population sequences and enables flexible remapping
eLife, 2015 Hippocampal place cells encode an animal's past, current, and future location through sequences of action potentials generated within each cycle of the network theta rhythm.
Angus Chadwick +2 more
doaj +1 more source
A learning rule for place fields in a cortical model: theta phase precession as a network effect
, 2005 We show that a model of the hippocampus introduced recently by Scarpetta, Zhaoping & Hertz ([2002] Neural Computation 14(10):2371-96), explains the theta phase precession phenomena.
Bi +22 more
core +1 more source
The double dipole model of theta rhythm generation: Simulation of laminar field potential profiles in dorsal hippocampus of the rat [PDF]
, 1982 A set of compartmental models of CA1 pyramidal, granular and polymorph cells of the dorsal hippocampus have been used to simulate membrane potentials generated by synaptic activation at various levels along these cells.
Boer, J. +3 more
core +2 more sources
Hard‐Magnetic Soft Millirobots in Underactuated Systems
Advanced Robotics Research, EarlyView.This review provides a comprehensive overview of hard‐magnetic soft millirobots in underactuated systems. It examines key advances in structural design, physics‐informed modeling, and control strategies, while highlighting the interplay among these domains.
Qiong Wang +4 more
wiley +1 more source
The Role of the Medial Septum—Associated Networks in Controlling Locomotion and Motivation to Move
Frontiers in Neural Circuits, 2021 The Medial Septum and diagonal Band of Broca (MSDB) was initially studied for its role in locomotion. However, the last several decades were focussed on its intriguing function in theta rhythm generation.
Petra Mocellin +2 more
doaj +1 more source
Enhancement of encoding and retrieval functions through theta phase-specific manipulation of hippocampus [PDF]
, 2017 Assessing the behavioral relevance of the hippocampal theta rhythm has proven difficult, due to a shortage of experiments that selectively manipulate phase-specific information processing.
Siegle, Joshua Handman +1 more
core +1 more source
Decoding Naturalistic Episodic Memory with Artificial Intelligence and Brain‐Machine Interface
Advanced Science, EarlyView.Episodic memory weaves together what, where, and when of experience into a personal narrative. Cutting‐edge AI models may decode this intricate process in real‐life settings, revealing how neural activity encodes naturalistic memories. By merging AI with brain–machine interfaces, researchers are edging closer to mapping and even engineering memory ...
Dong Song
wiley +1 more source
Brain–computer interface game applications for combined neurofeedback and biofeedback treatment for children on the autism spectrum [PDF]
, 2014 Individuals with Autism Spectrum Disorder (ASD) show deficits in social and communicative skills, including imitation, empathy, and shared attention, as well as restricted interests and repetitive patterns of behaviors.
Friedrich, Elisabeth V. C. +5 more
core +4 more sources
The modulation of hippocampal theta rhythm by the vestibular system [PDF]
Journal of Neurophysiology, 2018 The vestibular system is a sensory system that has evolved over millions of years to detect acceleration of the head, both rotational and translational, in three dimensions. One of its most important functions is to stabilize gaze during unexpected head movement; however, it is also important in the control of posture and autonomic reflexes.
Phillip, Aitken +2 more
openaire +2 more sources