Results 121 to 130 of about 1,817,384 (272)

Influence of body position on diaphragmatic thickening fraction in healthy adults: advancing the standardization of diaphragm ultrasonography

open access: yesFrontiers in Physiology
IntroductionThe diaphragm is the main respiratory muscle, and its dysfunction—particularly in hospitalized patients or those in intensive care units—is associated with difficulties in weaning from mechanical ventilation, functional deterioration, and ...
Leonardo Arzayus-Patiño   +7 more
doaj   +1 more source

Turbulent channel flow of dense suspensions of neutrally-buoyant spheres

open access: yes, 2015
Dense particle suspensions are widely encountered in many applications and in environmental flows. While many previous studies investigate their rheological properties in laminar flows, little is known on the behaviour of these suspensions in the ...
Brandt, L., Breugem, W. -P., Picano, F.
core   +1 more source

Establishment of a coculture system for Porphyromonas gingivalis and head and neck squamous cell carcinoma using spheroid culture and LATS inhibition

open access: yesFEBS Open Bio, EarlyView.
We established a spheroid coculture system enabling viable Porphyromonas gingivalis–HNSCC interactions under normoxic conditions. Inhibition of LATS1/2 maintains tumor cells in an undifferentiated state, which may promote spheroid growth and create a more permissive environment for bacterial persistence.
Yurika Nakajima   +4 more
wiley   +1 more source

Shear banding, discontinuous shear thickening, and rheological phase transitions in athermally sheared frictionless disks

open access: yes, 2017
We report on numerical simulations of simple models of athermal, bidisperse, soft-core, massive disks in two dimensions, as a function of packing fraction $\phi$, inelasticity of collisions as measured by a parameter $Q$, and applied uniform shear strain
Olsson, Peter   +2 more
core   +1 more source

The Importance of Measuring the Fraction of Diaphragmatic Thickening in Patients with COPD

open access: yesGlobal Journal of Medical and Clinical Case Reports
In addition to affecting the respiratory system, chronic obstructive pulmonary disease also decreases muscle mass. The respiratory muscles weaken, which impairs ventilation and exercise tolerance. According to recent studies, ultrasonography is a dependable and user-friendly method for determining the diaphragm thickening fraction (TFdi) in patients ...
Meridj Amine   +2 more
openaire   +1 more source

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

open access: yesFEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava   +3 more
wiley   +1 more source

Asymmetric exclusion processes with constrained dynamics

open access: yes, 2008
Asymmetric exclusion processes with locally reversible kinetic constraints are introduced to investigate the effect of non-conservative driving forces in athermal systems.
G. M. Schütz   +2 more
core   +1 more source

Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment

open access: yesAging and Cancer, EarlyView.
Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey   +12 more
wiley   +1 more source

Insights Into the Antigenic Repertoire of Unclassified Synaptic Antibodies

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective We sought to characterize the sixth most common finding in our neuroimmunological laboratory practice (tissue assay‐observed unclassified neural antibodies [UNAs]), combining protein microarray and phage immunoprecipitation sequencing (PhIP‐Seq). Methods Patient specimens (258; 133 serums; 125 CSF) meeting UNA criteria were profiled;
Michael Gilligan   +22 more
wiley   +1 more source

Post‐COVID Fatigue Is Associated With Reduced Cortical Thickness After Hospitalization

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Neuropsychiatric symptoms are among the most prevalent sequelae of COVID‐19, particularly among hospitalized patients. Recent research has identified volumetric brain changes associated with COVID‐19. However, it currently remains poorly understood how brain changes relate to post‐COVID fatigue and cognitive deficits.
Tim J. Hartung   +190 more
wiley   +1 more source

Home - About - Disclaimer - Privacy