Results 121 to 130 of about 1,817,384 (272)
IntroductionThe diaphragm is the main respiratory muscle, and its dysfunction—particularly in hospitalized patients or those in intensive care units—is associated with difficulties in weaning from mechanical ventilation, functional deterioration, and ...
Leonardo Arzayus-Patiño +7 more
doaj +1 more source
Turbulent channel flow of dense suspensions of neutrally-buoyant spheres
Dense particle suspensions are widely encountered in many applications and in environmental flows. While many previous studies investigate their rheological properties in laminar flows, little is known on the behaviour of these suspensions in the ...
Brandt, L., Breugem, W. -P., Picano, F.
core +1 more source
We established a spheroid coculture system enabling viable Porphyromonas gingivalis–HNSCC interactions under normoxic conditions. Inhibition of LATS1/2 maintains tumor cells in an undifferentiated state, which may promote spheroid growth and create a more permissive environment for bacterial persistence.
Yurika Nakajima +4 more
wiley +1 more source
We report on numerical simulations of simple models of athermal, bidisperse, soft-core, massive disks in two dimensions, as a function of packing fraction $\phi$, inelasticity of collisions as measured by a parameter $Q$, and applied uniform shear strain
Olsson, Peter +2 more
core +1 more source
The Importance of Measuring the Fraction of Diaphragmatic Thickening in Patients with COPD
In addition to affecting the respiratory system, chronic obstructive pulmonary disease also decreases muscle mass. The respiratory muscles weaken, which impairs ventilation and exercise tolerance. According to recent studies, ultrasonography is a dependable and user-friendly method for determining the diaphragm thickening fraction (TFdi) in patients ...
Meridj Amine +2 more
openaire +1 more source
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava +3 more
wiley +1 more source
Asymmetric exclusion processes with constrained dynamics
Asymmetric exclusion processes with locally reversible kinetic constraints are introduced to investigate the effect of non-conservative driving forces in athermal systems.
G. M. Schütz +2 more
core +1 more source
Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment
Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey +12 more
wiley +1 more source
Insights Into the Antigenic Repertoire of Unclassified Synaptic Antibodies
ABSTRACT Objective We sought to characterize the sixth most common finding in our neuroimmunological laboratory practice (tissue assay‐observed unclassified neural antibodies [UNAs]), combining protein microarray and phage immunoprecipitation sequencing (PhIP‐Seq). Methods Patient specimens (258; 133 serums; 125 CSF) meeting UNA criteria were profiled;
Michael Gilligan +22 more
wiley +1 more source
Post‐COVID Fatigue Is Associated With Reduced Cortical Thickness After Hospitalization
ABSTRACT Objective Neuropsychiatric symptoms are among the most prevalent sequelae of COVID‐19, particularly among hospitalized patients. Recent research has identified volumetric brain changes associated with COVID‐19. However, it currently remains poorly understood how brain changes relate to post‐COVID fatigue and cognitive deficits.
Tim J. Hartung +190 more
wiley +1 more source

