Results 71 to 80 of about 591,149 (264)

Detection of Differences in Longitudinal Cartilage Thickness Loss Using a Deep-Learning Automated Segmentation Algorithm: Data From the Foundation for the National Institutes of Health Biomarkers Study of the Osteoarthritis Initiative. [PDF]

Arthritis Care Res (Hoboken), 2022
Eckstein F, Chaudhari AS, Fuerst D, Gaisberger M, Kemnitz J, Baumgartner CF, Konukoglu E, Hunter DJ, Wirth W.   +8 more
europepmc   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Treatment with KCL‐286, a first‐in‐class retinoic acid receptor‐β (RARβ) agonist, ameliorates neuronal DNA damage and inflammation in a mouse model of Alzheimer's disease

FEBS Open Bio, EarlyView.
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill, Hassan Yousef Othman AlMuallim, Elouisa Maddock, Carl Hobbs, Earl Clarke, Maria B. Goncalves, Jonathan P. T. Corcoran   +6 more
wiley   +1 more source

A new flow chip in combination with multiphoton microscopy as a protocol for longitudinal 3D imaging of tissue calcification under shear stress

FEBS Open Bio, EarlyView.
Miniaturized flow chip platform enabling continuous perfusion and longitudinal multiphoton 3D imaging of vascular smooth muscle cell constructs under physiological flow. Brightfield imaging guides region selection, while CellTracker Green and mRuby‐labeled fetuin‐A visualize cells and mineral deposition, respectively. Magnesium supplementation markedly
Vytautas Kučikas, Aaron D. Morgan, Ignas Čiurlionis, Christian Böhm, Stefan Jockenhövel, Willi Jahnen‐Dechent, Marc A. M. J. van Zandvoort   +6 more
wiley   +1 more source

Explainable ensemble models for predicting wall thickness loss of water pipes

Ain Shams Engineering Journal
Water Distribution Networks (WDNs) are susceptible to pipe failures with significant consequences. Predicting wall-thickness loss in pipes is vital for proactive maintenance and asset management.
Ridwan Taiwo, Abdul-Mugis Yussif, Mohamed El Amine Ben Seghier, Tarek Zayed   +3 more
doaj   +1 more source

Purification and preparation of Marchantia polymorpha Auxin Response Factor 2 for phase separation studies

FEBS Open Bio, EarlyView.
We describe detailed protocols for the purification and preparation of Marchantia polymorpha Auxin Response Factor 2 (MpARF2). This protein is fused to an MBP solubility tag and an mNG fluorescent tag and is purified from Escherichia coli. The presented procedures make it possible to study MpARF2 assemblies, which could arise from phase separation ...
Bas Janssen, Robin Romein, Willy A. M. van den Berg, Simon Lindhoud, Jan Willem Borst, Carlo P. M. van Mierlo   +5 more
wiley   +1 more source

De novo synthesis of short‐chain aldehydes and hydrocarbons secreted by the brown marmorated stink bug Halyomorpha halys

FEBS Open Bio, EarlyView.
The brown marmorated stink bug, Halyomorpha halys, mainly secretes 4‐oxo‐(E)‐2‐hexenal, (E)‐2‐decenal, dodecane and tridecane, a mixture representative of that released by many heteropterans. We demonstrated that H. halys can synthesise these secretory components de novo using dietary glucose.
Haruna Fujimori, Koji Noge
wiley   +1 more source

Evaluating the relationship between periodontal bone loss in maxillary posterior teeth and Schneiderian membrane thickness

BMC Oral Health
Background To understand the potential impact of periodontal disease on maxillary sinus health, this study aimed to evaluate the relationship between periodontal bone loss and maxillary sinus membrane thickness using cone beam computed tomography (CBCT).
Cemre Ekşi, Başak Şeker
doaj   +1 more source

Superficial Vessel Density, Retinal Nerve Fiber Layer Thickness, and Visual Field Loss in Primary Open-Angle and Pseudoexfoliative Glaucoma

Acta Clinica Croatica
The aim was to examine peripapillary and macular superficial vessel density, peripapillary thickness of the nerve fiber layer, and inner thickness of the macula in eyes with primary open-angle glaucoma (POAG) and pseudoexfoliative glaucoma (PXG ...
Ante Prpić, Iva Ferček, Kim Kasa, Armin Kasumović, Ines Matoc, Idoia Goñi Guarro, Vedrana Vukić, Katia Novak-Lauš, Ivan Sabol, Zoran Vatavuk   +9 more
doaj   +1 more source

Energy-loss- and thickness-dependent contrast in atomic-scale electron energy-loss spectroscopy

Physical Review B, 2014
Atomic-scale elemental maps of materials acquired by core-loss inelastic electron scattering often exhibit an undesirable sensitivity to the unavoidable elastic scattering, making the maps counterintuitive to interpret. Here, we present a systematic study that scrutinizes the energy-loss and sample-thickness dependence of atomic-scale elemental maps ...
Tan, Haiyan, Zhu, Ye, Dwyer, Christian, Xin, Huolin   +3 more
openaire   +3 more sources