Immune-related gene signatures of thin endometrium: a transcriptomic and single-cell study. [PDF]
Front Endocrinol (Lausanne)Background Thin endometrium (TE) is associated with impaired endometrial receptivity and reduced rates of successful pregnancy. However, the immune-related transcriptomic alterations underlying TE remain poorly understood.
Niu Y, Le A.
europepmc +2 more sources
The effect of endometrial PRP on fertility outcomes in women with implantation failure or thin endometrium. [PDF]
Arch Gynecol ObstetTo evaluate the effect of intrauterine platelet-rich plasma (PRP) treatment on frozen–thawed embryo transfer (FET) cycles in patients with recurrent implantation failure. The study group consisted of 150 patients.
Gurkan N, Alper T.
europepmc +2 more sources
Impaired receptivity of thin endometrium: therapeutic potential of mesenchymal stem cells. [PDF]
Front Endocrinol (Lausanne), 2023 The endometrium is a resilient and highly dynamic tissue, undergoing cyclic renewal in preparation for embryo implantation. Cyclic endometrial regeneration depends on the intact function of several cell types, including parenchymal, endothelial, and ...
Saad-Naguib MH +4 more
europepmc +2 more sources
hUC-MSCs loaded collagen scaffold for refractory thin endometrium caused by Asherman syndrome: a double-blind randomized controlled trial. [PDF]
Stem Cells Transl MedIn this single-center, double-blinded, randomized controlled trial, we investigated whether human umbilical cord-derived mesenchymal stromal cells loaded collagen scaffolds (hUC-MSC/CS) could improve the cumulative live-birth rate (cLBR) in infertile ...
Hou Z +14 more
europepmc +2 more sources
Network meta-analysis on the efficacy of different interventions for treating thin endometrium. [PDF]
Front Endocrinol (Lausanne)Background The incidence of thin endometrium in assisted reproductive technology (ART) is between 1% and 2.5%, yet its treatment options are varied and often show limited efficacy.
Keng F +8 more
europepmc +2 more sources
Comprehensive single-cell transcriptome analysis of autologous platelet-rich plasma therapy on human thin endometrium. [PDF]
Sci RepTherapeutics for thin endometrium (TE) have emerged, with autologous platelet-rich plasma (PRP) therapy gaining significant attention. In the present study, ten eligible TE patients were recruited for PRP infusion.
Zeng J +5 more
europepmc +2 more sources
Impact of platelet-rich plasma intrauterine perfusion on endometrial receptivity and pregnancy outcomes in patients with recurrent implantation failure and thin endometrium. [PDF]
Am J Transl ResOBJECTIVES To evaluate the impact of autologous platelet-rich plasma (PRP) intrauterine perfusion on endometrial receptivity and pregnancy outcomes in patients with implantation failure.
Peng F +5 more
europepmc +2 more sources
Etiological and associated factors of thin endometrium among infertile women. [PDF]
BioinformationThin endometrium is a condition that adversely affects infertility treatment outcomes by impairing embryo implantation and pregnancy success. Therefore, it is of interest to assess the etiological and associated factors of thin endometrium in 61 women ...
Rani K +4 more
europepmc +2 more sources
Platelet-rich plasma therapy for thin endometrium: a comprehensive review. [PDF]
Arch Gynecol ObstetThin endometrium (TE) is a significant limiting factor for successful in vitro fertilization (IVF) and embryo transfer (ET), often resulting in poor pregnancy outcomes. Current therapeutic options remain limited and inconsistent in efficacy.
Yang Y, Zhang X, Zhang Y.
europepmc +2 more sources
Dysfunctional intercellular communication and metabolic signaling pathways in thin endometrium
Frontiers in Physiology, 2022 Background: The endometrial thickness is a key factor for successful implantation. Thin endometrium is associated with lower implantation rate and pregnancy rate.
Liang Xu +3 more
doaj +3 more sources