Results 81 to 90 of about 319,151 (294)

Immune Checkpoint Inhibitors and Immunomodulators for Cancer Immunotherapy: Insights Into Resistance and Therapeutic Strategies

Advanced Science, EarlyView.
The schematic diagram illustrates the roles of novel immune checkpoints, immunomodulatory factors, cell death and multimodal technologies in cancer immunotherapy. Abstract Cancer immunotherapy has redefined cancer treatment. However, the molecular and cellular basis of immune evasion and therapeutic resistance remains incompletely understood.
Fangquan Chen, Yang Yu, Xiutao Cai, Junhao Lin, Ruirui Liang, Rui Kang, Daolin Tang, Jiao Liu   +7 more
wiley   +1 more source

Urban green spaces and healthy aging: the role of physical activity

Frontiers in Public Health
BackgroundAgainst the backdrop of ongoing urban renewal and the Healthy China initiative, examining the relationship between urban green spaces, physical activity, and healthy aging among residents holds significant importance for advancing urban health ...
Xu Wang, Chengyue Li, Xuguang Wang
doaj   +1 more source

On History and Liberty: The ‘Revisionism’ of Bronisław Baczko [PDF]

, 2017
The ‘Warsaw School of History of Ideas’ is the name given to a ‘revisionist think tank’ which was led by the historian Bronisław Baczko from 1956 to 1968 in Communist Poland.
Baiao, Helder Mendes
core  

Dual Covalent Targeting of STING Cysteines 292/309 Disrupts Functional Oligomerization and Enables Potent Antagonist Development

Advanced Science, EarlyView.
We report a rational design strategy for STING antagonists by dual covalent targeting of Cys292/309 in its C‐terminal domain, directly preventing functional oligomerization. Through covalent warhead repurposing, we identified P005091 and revealed its unique dual‐cysteine mechanism.
Yuxuan Zhao, Ling Huang, Wenjing Qin, Bin Zhang, Yang Yang, Xue Chen, Xiaoquan Wang, Weilin Zhou, Feiyang Chen, Zhenyu Li, Liyuan Le, Yiqiu Zhang, Zhen Xiang, Lu Zhang, Fei Wang, Dan Lei, Zi‐zhe Cai, Ying Gao, Yong Chen, Xuecen Wang, Junmin Quan, Shuixing Zhang, Xianzhang Bu, Xin Yue   +23 more
wiley   +1 more source

Think Tank [PDF]

AORN Journal, 2005
openaire   +2 more sources

Developing a framework for estimating comorbidity burden of inpatient cancer patients based on a case study in China

Global Health Research and Policy
Inpatient cancer patients often carry the dual burden of the cancer itself and comorbidities, which were recognized as one of the most urgent global public health issues to be addressed.
Jiamin Wang, Wenjing Zhang, Kexin Sun, Mingzhu Su, Yuqing Zhang, Jun Su, Xiaojie Sun   +6 more
doaj   +1 more source

The Changing Conceptual Landscape of the Russian War in Ukraine (2014-Present) and Syria (2011-Present)

Journal of Liberty and International Affairs
The main goal of this paper is to present and compare the main developments in the Russian wars in Ukraine and Syria by considering the main patterns, parallels, and changing trajectories that could shed more light onto both of these war zones, which ...
Piotr Pietrzak
doaj   +1 more source

Pellet Printing for Soft Robotic Devices

Advanced Science, EarlyView.
Fused Granulate Fabrication (FGF) is established here as a reliable method for fabricating soft, airtight robotic devices. Through coordinated optimization of hardware, material selection, and process parameters, this approach enables high‐speed printing of thermoplastic elastomers with silicone‐like softness and modulus.
Yijia Wu, Ju‐Hung Chen, Ariana Olivares, Katherine Kostak, Stefan Pedicone, Savita V. Kendre, Markus P. Nemitz   +6 more
wiley   +1 more source

The impact of English usage on social media on college students’ interpersonal communication intentions: a dual mediating model of language confidence and English cultural identity

Frontiers in Psychology
IntroductionSocial media has become part of daily life in the era of globalization and the swift development of internet technology. The worldwide user base is expected to go over 4 billion by 2024, radically transforming social interaction patterns ...
Yichao Zhang, Yichao Zhang, Yiming Wu, Yiming Wu, Yanjun Chen, Hongtao Zhang   +5 more
doaj   +1 more source

Tri‐Layer Solid‐State Nanopore Arrays with Crosstalk Suppression for High‐Throughput, Femtomolar‐Level Biosensing

Advanced Science, EarlyView.
The critical pore spacing—approximately twenty times the pore radius—required to minimize electric field coupling is determined via finite element analysis. A multi‐layered Al2O3/Au/Si3N4 nanopore structure fabricated by helium ion beam lithography is proposed, enabling quantitative analysis of the target analyte while mitigating inter‐pore crosstalk ...
Silu Feng, Qinglong Luo, Siqi Ai, Suiwei Shen, Chengyong Wang, Zhishan Yuan   +5 more
wiley   +1 more source