Results 91 to 100 of about 207,570 (288)

The think tanks roll [PDF]

open access: yesBMJ, 1988
Sounds of protest from demonstrating nurses and health workers on their "day of action" penetrated the Commons committee room where the social services select committee was grappling sedately with the same issue. Each in its fashion is part of the democratic process, though it is arguable which has more impact on the government. But in a week that also
openaire   +2 more sources

Engineering New‐to‐Nature Biological Pathways for β,γ‐Alkanediol Synthesis

open access: yesAdvanced Science, EarlyView.
β,γ‐Alkanediols are value‐added chemicals to be used as functional solvents, biofuels, and cosmetic components. This work demonstrates a carboligation‐mediated approach for synthesis of linear chain β,γ‐alkanediols in Escherichia coli, namely, hexane‐2,3‐diol (2,3‐HDO) and pentane‐2,3‐diol (2,3‐PDO). The engineered E. coli cells produce 152.2 mm (17.98
Haofeng Chen   +6 more
wiley   +1 more source

Content management on YouTube by Spanish think tanks

open access: yesFrontiers in Political Science
The growing need for think tanks to effectively manage their communication in order to reach their stakeholders has forced them to implement communication strategies that go beyond offline media.
Ruth Gómez de Travesedo-Rojas   +1 more
doaj   +1 more source

Neuronal Cholesterol Deficiency Mediated by Astrocytic SREBP2 Downregulation Leads to Postoperative Cognitive Dysfunction Through Impairment of Hippocampal Synaptic Plasticity and Excitatory Synaptic Transmission

open access: yesAdvanced Science, EarlyView.
The results showed that the reduction of plasma 24‐hydroxycholesterol (24‐OHC) was related to the cognitive decline in elderly surgical patients. Neuroinflammation induced by anesthesia and surgery significantly downregulated SREBP2 in hippocampal reactive astrocytes, resulting in reduced cholesterol synthesis.
He Huang   +13 more
wiley   +1 more source

Hepatocyte BDNF Acts as a Novel Immune Checkpoint to Restrain TLR4‐Mediated Acute Hepatitis

open access: yesAdvanced Science, EarlyView.
This study identifies hepatocyte‐derived BDNF as an endogenous TLR4 antagonist that alleviates acute hepatitis. BDNF is downregulated in hepatocytes via REST‐mediated transcriptional repression during ALI/ALF. Mechanistically, BDNF binds to TLR4 on macrophages to suppress inflammation.
Weiwei Zhu   +15 more
wiley   +1 more source

Think tanks, evidence and policy: democratic players or clandestine lobbyists? [PDF]

open access: yes, 2017
Depending on your perspective, think tanks either enrich the democratic space by conducting policy research and facilitating public dialogue and debate, or undermine democracy by pushing policies favoured by powerful corporate interests.
Bruckner, Till
core  

International cooperation against climate change: institutions, policies and their efficiency [PDF]

open access: yes, 2012
In the 20th century nature of the world economy has started to change significantly, and the former state-centric constellation disappeared. Several development factors that induced the change are still active and nowadays we live in a much different ...
Tőrös, Ágnes
core  

Real‐Time Digital Micromotor Tracking‐Enabled Ultrasensitive Immunoassay

open access: yesAdvanced Science, EarlyView.
An AI‐facilitated real‐time digital micromotor tracking‐enabled immunoassay is developed, which leverages a self‐developed multi‐microparticle tracking system to monitor micromotor motion trajectories in a real‐time manner for digital protein analysis.
Jingjing Shi   +6 more
wiley   +1 more source

Book review: how think tanks shape social development policies, edited by James McGann, Jillian Rafferty, and Anna Viden [PDF]

open access: yes, 2014
Across the globe, there are more than four thousand policy institutes or think tanks that research or advocate for economic and social development. Yet the relationship between these organizations and the policies they influence is not well understood ...
Gonzalez Hernando, Marcos
core  

Immune Checkpoint Inhibitors and Immunomodulators for Cancer Immunotherapy: Insights Into Resistance and Therapeutic Strategies

open access: yesAdvanced Science, EarlyView.
The schematic diagram illustrates the roles of novel immune checkpoints, immunomodulatory factors, cell death and multimodal technologies in cancer immunotherapy. Abstract Cancer immunotherapy has redefined cancer treatment. However, the molecular and cellular basis of immune evasion and therapeutic resistance remains incompletely understood.
Fangquan Chen   +7 more
wiley   +1 more source

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