Results 171 to 180 of about 1,125,240 (316)

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

FEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner, Hainan Zhu, Carol Christine Bosholm, Heuy‐Ching Wang, Tracy Criswell, Anthony Atala, Jian‐Xing Ma, Yuanyuan Zhang   +7 more
wiley   +1 more source

Housing and systems thinking

, 2019
This working paper outlines the value of using systems thinking concepts to frame understanding of the housing sector. The UK Collaborative Centre for Housing Evidence (CaCHE) was funded in part on the basis that it would, where appropriate, integrate ...
Gibb, Ken, Marsh, Alex
core  

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

FEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young, Omar Arias‐Gaguancela, Fiona Gibson, Morgan Grainger, Jodie Score, Amit Nathubhai, Mauricio Cafiero, Lee Richard Machado   +7 more
wiley   +1 more source

The Relationship between parental emotional support and geospatial thinking ability: a moderated mediating model. [PDF]

Front Psychol
Wang L, Liu L, Meng X, Wang L, Ma W.
europepmc   +1 more source

Chess players' thinking revisited

, 1998
The main result of De Groot’s ([1946] 1978) classical study of chessplayers’ thinking was that players of various levels of skill do not differ in the macrostructure of their thought process (in particular with respect to the depth of search and to the ...
Gobet, F
core  

Sudden anaerobization in Amphibacillus xylanus increases intracellular labile ferrous iron and inhibits cell growth

FEBS Open Bio, EarlyView.
Abruptly changing from aerobic to anaerobic conditions (sudden anaerobization) induced growth inhibition and a significant increase in intracellular labile ferrous iron in the aerotolerant anaerobe Amphibacillus xylanus. We found that free flavins mediate efficient electron transfer from NADH to ferric iron under anaerobic conditions, suggesting that ...
Shinya Kimata, Yoichi Sakai, Keisuke Tanaka, Etsuro Yoshimura, Ken Kitano, Morio Ishikawa, Tadahiro Nakamoto, Tsutomu Takayama, Hirofumi Inoue, Kaho Nomura, Tomonori Suzuki, Masataka Uchino, Akira Abe, Youichi Niimura   +13 more
wiley   +1 more source

How do we think and what is the neural circuit mechanism for it? Possible roles of working memory and inner speech in thinking. [PDF]

Front Hum Neurosci
Mori K, Sakano H.
europepmc   +1 more source

The Potency Of Metacognitive Learning To Foster Mathematical Logical Thinking

, 2011
The ability of thinking logically needs to be developed due to the fact that it is an essential basic skill. Logical thinking affects that giving reason must be true, and that a sequence of assumptions is based on the high truth value.
Jozua , Sabandar, Mimih , Aminah
core  

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

FEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour, Christine Volmert, Valentina Piano   +2 more
wiley   +1 more source

Will the widespread use of large language models in scientific writing undermine scientists' critical thinking? [PDF]

PLoS Biol
Bietti LM, Bangerter A.
europepmc   +1 more source