Results 141 to 150 of about 674,206 (305)

Emerging role of ARHGAP29 in melanoma cell phenotype switching

Molecular Oncology, EarlyView.
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster, Melanie Kappelmann‐Fenzl, Anja Katrin Bosserhoff, Nicole Rachinger   +3 more
wiley   +1 more source

Screening for lung cancer: A systematic review of overdiagnosis and its implications

Molecular Oncology, EarlyView.
Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...
Fiorella Karina Fernández‐Sáenz, Laura de la Torre‐Perez, David R Baldwin, Carlijn van der Aalst, Mangesh Thorat, David Ritchie, Andre L Carvalho, Carolina Espina, Ivan Solà, Carlos Canelo‐Aybar, Moira Magdalena Pissinis, Pablo Alonso‐Coello, Ana Carolina Pereira Nunes Pinto   +12 more
wiley   +1 more source

HOTS Geometry Analysis on Critical Thinking and Numeracy Skills Reviewed Learning Style and Gender

Edumatica: Jurnal Pendidikan Matematika
Critical thinking and numeracy skills are important competencies for students facing challenges of the 21st century and era of industrial revolution 5.0.
Nanang Diana, Agustinasari Agustinasari, Husnul Khatimah, M. Ibnusaputra, Adi Apriadi Adiansha, Muslim Muslim   +5 more
doaj   +1 more source

Mood-congruent negative thinking styles and cognitive vulnerability in depressed COVID-19 survivors: A comparison with major depressive disorder. [PDF]

J Affect Disord, 2022
Benedetti F, Palladini M, D'Orsi G, Furlan R, Ciceri F, Rovere-Querini P, COVID-19 BioB Outpatient Clinic Study group, Mazza MG.   +7 more
europepmc   +1 more source

Glycosylated LGALS3BP is highly secreted by bladder cancer cells and represents a novel urinary disease biomarker

Molecular Oncology, EarlyView.
Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece, Giulio Lovato, Ilaria Cela, Arianna Mercatelli, Benedetta Ferro, Jussi Nikkola, Sara Pagotto, Tommaso Grottola, Vincenzo De Laurenzi, Rossella Cicchetti, Antonio Marchetti, Luigi Schips, Rossano Lattanzio, Stefano Iacobelli, Emily Capone, Peter Black, Mads Daugaard, Michele Marchioni, Gianluca Sala   +18 more
wiley   +1 more source

Reversible thinking in solving mathematics problems in terms of cognitive style

Al-Jabar
Background: Reversible thinking, the ability to think bidirectionally, is a crucial component of mathematical problem-solving. Differences in cognitive styles, particularly field-dependent and field-independent characteristics, play a significant role in
Hakmi Rais Fauzan, Erry Hidayanto, Tjang Daniel Chandra   +2 more
doaj   +1 more source

Understanding systems thinking:an agenda for applied research in industry [PDF]

, 2012
Why systems thinking is valuable is relatively easy to explain.  However, in the authors’ work as university educators, teaching a student processes of enquiry that are themselves systemic is a difficult undertaking.  The capacity to view
Buckle Henning, Pamela, Wilmshurst, Jacqui, Yearworth, Mike   +2 more
core  

Survivin and Aurora Kinase A control cell fate decisions during mitosis

Molecular Oncology, EarlyView.
Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir, Shalitha Wickrama Arachchige, Sally P. Wheatley   +2 more
wiley   +1 more source

THE PROFILE OF STUDENTS’ LATERAL THINKING IN SOLVING MATHEMATICS OPEN-ENDED PROBLEM IN TERMS OF LEARNING STYLE DIFFERENCES [PDF]

, 2014
In this globalization era, students as young generation of a country must be creative an innovative. As well as that, in solving mathematics problems, students should be able to find out several alternatives of questions or it is well -
Nicky, Puspaningtyas
core  

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

Molecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir, Lukasz Arcimowicz, Lucia Martinkova, Vaclav Hrabal, Filip Zavadil Kokas, Tomas Henek, Martina Kucerikova, Ondrej Bonczek, Pavlina Zatloukalova, Lenka Hernychova, Philip J. Coates, Borivoj Vojtesek, David P. Lane   +12 more
wiley   +1 more source